tetrapyrrole biosynthesis II
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.3.1.37 | 5-aminolevulinate synthase | succinyl-CoA:glycine C-succinyltransferase (decarboxylating) | |
| 2.5.1.61 | hydroxymethylbilane synthase | porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing) | |
| 4.2.1.24 | porphobilinogen synthase | 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming) | |
| 4.2.1.75 | uroporphyrinogen-III synthase | hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P05373 | HEM2 | Delta-aminolevulinic acid dehydratase |
| P06174 | HEM4 | Uroporphyrinogen-III synthase |
| P09950 | HEM1 | 5-aminolevulinate synthase, mitochondrial |
| P28789 | HEM3 | Porphobilinogen deaminase |