myricetin gentiobioside biosynthesis

Vepsäläinen S, Koivisto H, Pekkarinen E, Mäkinen P, Dobson G, McDougall GJ, Stewart D, Haapasalo A, Karjalainen RO, Tanila H, Hiltunen M. Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease. The Journal of Nutritional Biochemistry. 2013 Jan;24(1):360–70. doi: 10.1016/j.jnutbio.2012.07.006.; Fiori J, Naldi M, Bartolini M, Andrisano V. Disclosure of a fundamental clue for the elucidation of the myricetin mechanism of action as amyloid aggregation inhibitor by mass spectrometry. Electrophoresis. 2012 Nov;33(22):3380–6. doi: 10.1002/elps.201200186. PMID: 22961751.; Chobot V, Hadacek F. Exploration of pro-oxidant and antioxidant activities of the flavonoid myricetin. Redox Report. 2011 Nov;16(6):242–7. doi: 10.1179/1351000211y.0000000015.; Kumar D, Kumar S, Gupta J, Arya R, Gupta A. A review on chemical and biological properties of Cayratia trifolia Linn. (Vitaceae). Pharmacogn Rev. 2011 Jul;5(10):184–8. PMID: 22279376; PMCID: PMC3263053.; Owens DK, McIntosh CA. Identification, recombinant expression, and biochemical characterization of a flavonol 3-O-glucosyltransferase clone from Citrus paradisi. Phytochemistry. 2009 Jul;70(11-12):1382–91. doi: 10.1016/j.phytochem.2009.07.027. PMID: 19733370.; Masada S, Terasaka K, Oguchi Y, Okazaki S, Mizushima T, Mizukami H. Functional and structural characterization of a flavonoid glucoside 1,6-glucosyltransferase from Catharanthus roseus. Plant Cell Physiol. 2009 Aug;50(8):1401–15. doi: 10.1093/pcp/pcp088. PMID: 19561332.; Oguchi Y, Masada S, Kondo T, Terasaka K, Mizukami H. Purification and characterization of UDP-glucose : curcumin glucoside 1,6-glucosyltransferase from Catharanthus roseus cell suspension cultures. Plant Cell Physiol. 2007 Nov;48(11):1635–43. doi: 10.1093/pcp/pcm138. PMID: 17940060.; TAHARA S. A Journey of Twenty-Five Years through the Ecological Biochemistry of Flavonoids. Bioscience, Biotechnology, and Biochemistry. 2007 Jun 23;71(6):1387–404. doi: 10.1271/bbb.70028.; Martens S, Mithöfer A. Flavones and flavone synthases. Phytochemistry. 2005 Oct;66(20):2399–407. doi: 10.1016/j.phytochem.2005.07.013. PMID: 16137727.; Vogt T, Jones P. Glycosyltransferases in plant natural product synthesis: characterization of a supergene family. Trends Plant Sci. 2000 Sep;5(9):380–6. doi: 10.1016/s1360-1385(00)01720-9. PMID: 10973093.

Metabolites

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

Diacetyl

Formula: C4H6O2 (86.0367776)

CAS ID: 431-03-8

Diethyl pyrocarbonate

Formula: C6H10O5 (162.052821)

CAS ID: 1609-47-8

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Tetranitromethane

Formula: CN4O8 (195.97161599999998)

CAS ID: 509-14-8

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

N-bromosuccinimide

Formula: C4H4BrNO2 (176.9425384)

CAS ID: 128-08-5



Enzyme

EC Number name full name note


Proteins

Protein ID name full name