methylglyoxal degradation I

Kalapos MP. Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications. Toxicol Lett. 1999 Nov 22;110(3):145–75. doi: 10.1016/s0378-4274(99)00160-5. PMID: 10597025.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Methylglyoxal

Formula: C3H4O2 (72.0211284)

CAS ID: 78-98-8

Ubiquinone-1

Formula: C14H18O4 (250.1205028)

CAS ID: 727-81-1

QH(2)

Formula: C14H20O4 (252.136152)

CAS ID: 52590-98-4

(R)-S-lactoylglutathionate(1-)

Formula: C13H20N3O8S (378.09710600000005)

CAS ID:

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3



Enzyme

EC Number name full name note
1.1.2.4 D-lactate dehydrogenase (cytochrome) (R)-lactate:ferricytochrome-c 2-oxidoreductase
3.1.2.6 hydroxyacylglutathione hydrolase S-(2-hydroxyacyl)glutathione hydrolase
4.4.1.5 lactoylglutathione lyase (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)


Proteins

Protein ID name full name