superpathway of pyrimidine ribonucleotides de novo biosynthesis

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

HCO3-

Formula: HCO3 (60.9925696)

CAS ID: 71-52-3

L-aspartate(1-)

Formula: C4H6NO4 (132.0296816)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.1.3.2 aspartate carbamoyltransferase carbamoyl-phosphate:L-aspartate carbamoyltransferase
2.7.4.22 UMP kinase ATP:UMP phosphotransferase
2.7.4.6 nucleoside-diphosphate kinase ATP:nucleoside-diphosphate phosphotransferase
4.1.1.23 orotidine-5'-phosphate decarboxylase orotidine-5'-phosphate carboxy-lyase (UMP-forming)
6.3.4.16 carbamoyl-phosphate synthase (ammonia) carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing) hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)


Proteins

Protein ID name full name
P58638 pyrF Orotidine 5'-phosphate decarboxylase
Q8UDE9 carB Carbamoyl phosphate synthase large chain
Q8UDF7 carA Carbamoyl phosphate synthase small chain
Q8UFM1 pyrH Uridylate kinase
Q8UFT9 pyrB Aspartate carbamoyltransferase catalytic subunit
Q8UGB6 ndk Nucleoside diphosphate kinase