2-Hydroxy-3-oxopropanoate (BioCAD00000002525)

microbial natural products

Metabolite Card

Formula: C3H4O4 (104.011)
SMILES: OC(C=O)C(O)=O

Synonyms [en]

Tartronate semialdehyde; 2-Hydroxy-3-oxopropanoate; 2-hydroxy-3-oxopropanoic acid; hydroxymalonaldehydic acid; tartronic semialdehyde; Formyl(hydroxyl)acetic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

2-Hydroxy-3-oxopropanoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000002525). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Tartronate semialdehyde is an intermediate in ascorbate and aldarate as well as glyoxylate and dicarboxylate metabolism. It is generated from 2-dehydro-3-deoxy-D-glucarate and 5-dehydro-4-deoxy-D-glucarate via the enzyme 2-dehydro-3-deoxyglucarate aldolase [EC:4.1.2.20].

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 2480-77-5
  • PubChem: 1122
  • ChEBI: ChEBI:16992
  • HMDB: HMDB0006938
  • HMDB: HMDB06938
  • KEGG: C01146
  • NCBI MeSH: tartronate semialdehyde
  • RefMet: RM0136326
  • Metlin: METLIN_58597
  • Coconut NaturalProduct: CNP0083603.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00013 4.1.1.47 glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)
KEGG:R01394 5.3.1.22 hydroxypyruvate aldose-ketose-isomerase
KEGG:R01745 1.1.1.60 (R)-glycerate:NAD+ oxidoreductase
KEGG:R01747 1.1.1.60 (R)-glycerate:NADP+ oxidoreductase
KEGG:R02754 4.1.2.20 5-dehydro-4-deoxy-D-glucarate tartronate-semialdehyde-lyase
KEGG:R03127 4.1.1.54 dihydroxyfumarate carboxy-lyase
KEGG:R03277 4.1.2.20 C01146 + C00022<=>C03921
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Organism Source

Taxonomy Source

  1. Escherichia coli [ncbi taxid: 562]
  2. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
BioCyc:TRYPANO_GLUCARDEG-PWY D-glucarate degradation I
BioCyc:TRYPANO_GLUCARGALACTSUPER-PWY superpathway of D-glucarate and D-galactarate degradation
BioCyc:TRYPANO_GALACTARDEG-PWY D-galactarate degradation I
PathBank:SMP0000816 D-Glucarate and D-Galactarate Degradation
PathBank:SMP0000847 Glycolate and Glyoxylate Degradation
PathBank:SMP0002035 Glycolate and Glyoxylate Degradation II
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-FVE-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-MES-2744345 Metabolism and regulation
Plant Reactome:R-MES-1119502 Allantoin assimilation
Plant Reactome:R-TDI-2744345 Metabolism and regulation
Plant Reactome:R-TDI-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-OGU-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-PTI-2744345 Metabolism and regulation
Plant Reactome:R-PTI-1119502 Allantoin assimilation
Plant Reactome:R-GMA-2744345 Metabolism and regulation
Plant Reactome:R-GMA-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-PDA-2744345 Metabolism and regulation
Plant Reactome:R-PVU-2744345 Metabolism and regulation
Plant Reactome:R-PVU-5096066 Amine and polyamine biosynthesis
View All Pathways