Metabolite Card
Formula: C4H9NO2 (103.0633)
SMILES: C[C@H](CN)C(O)=O
Synonyms [en]
(R)-3-Amino-2-methylpropanoate; D-3-Amino-isobutanoate; 2R-methyl-3-amino-propanoic acid; (R)-beta-aminoisobutyrate; (R)-3-aminoisobutyrate; (2R)-3-amino-2-methylpropanoic acid
Last reviewed on 2024-06-28.
Cite this Page
(R)-3-Amino-2-methylpropanoate. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000000834). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
(R)-beta-Aminoisobutyric acid is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase (DPD), in what constitutes the first step of the pyrimidine degradation pathway. The other product of the reaction is beta-alanine (PMID: 14705962).
DBLinks
- CAS Registry Number: 2140-95-6
- PubChem CID: 5459822
- ChEBI: 16320
- HMDB: HMDB0002299
- LipidMaps: LMFA01100049
- KEGG: C01205
- BioCyc: CPD-471
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- CAS Registry Number: 2140-95-6
- PubChem: 5459822
- ChEBI: ChEBI:16320
- HMDB: HMDB0002299
- LipidMaps: LMFA01100049
- KEGG: C01205
- BioCyc: CPD-471
- Metlin: METLIN_45883
- Coconut NaturalProduct: CNP0291505.2
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- LipidMaps: [Amino fatty acids [FA0110]] Amino fatty acids [FA0110]
- ChEBI: [CHEBI:16320] (R)-3-aminoisobutyric acid
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R02050 | 2.6.1.40 | (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase |
| KEGG:R04666 | 3.5.1.6 | (R)-3-ureidoisobutyrate amidohydrolase |
| BioCyc:2.6.1.40-RXN | 2.6.1.40 | PYRUVATE + CPD-471<=>L-ALPHA-ALANINE + CH3-MALONATE-S-ALD |
| BioCyc:RXN-11210 | 3.5.1.6 | 3-UREIDO-ISOBUTYRATE + WATER + 2 PROTON --> CPD-471 + AMMONIUM + CARBON-DIOXIDE |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP3604 | Biochemical pathways: part I |
| WikiPathways:WP4022 | Pyrimidine metabolism |