Calcitetrol (BioCAD00000007825)

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Metabolite Card

Formula: C27H44O4 (432.3239)
SMILES: [H][C@@]1(CC[C@@]2([H])\\C(CCC[C@]12C)=C\\C=C1\\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CC[C@@H](O)C(C)(C)O

Synonyms [en]

calcitetrol; (1S,3R,5Z,7E,24R,25)-9,10-secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol; (24R)-24-Hydroxycalcitriol; 1alpha,24R,25-trihydroxyvitamin D3; 1,24,25-trihydroxyvitamin D3; 1alpha,24R,25-trihydroxycholecalciferol

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Calcitetrol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000007825). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Calcitetrol is a hydroxycalciol. It has a role as a human metabolite. Calcitetrol is a natural product found in Homo sapiens and Ambystoma mexicanum with data available.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 50648-94-7
  • CAS Registry Number: 56142-94-0
  • CAS Registry Number: 72203-93-1
  • PubChem: 6446280
  • PubChem: 73950788
  • PubChem: 9910685
  • ChEBI: ChEBI:47799
  • HMDB: HMDB0006228
  • LipidMaps: LMST03020686
  • KEGG: C18231
  • BioCyc: CPD-10577
  • NCBI MeSH: 1,24,25-trihydroxyvitamin D3
  • Metlin: METLIN_57898
  • Coconut NaturalProduct: CNP0082820.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R09515 1.14.15.16 calcitriol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating)
KEGG:R11324 1.14.15.18 secalciferol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating)
Rhea:RHEA:24965 1.14.15.16 calcitriol + 2 reduced [adrenodoxin] + O2 + 2 H+ => calcitetrol + 2 oxidized [adrenodoxin] + H2O
Rhea:RHEA:24966 1.14.15.16 calcitetrol + 2 oxidized [adrenodoxin] + H2O => calcitriol + 2 reduced [adrenodoxin] + O2 + 2 H+
Rhea:RHEA:24967 1.14.15.16 calcitriol + 2 reduced [adrenodoxin] + O2 + 2 H+ <=> calcitetrol + 2 oxidized [adrenodoxin] + H2O
Rhea:RHEA:24973 1.14.15.16 calcitetrol + 2 reduced [adrenodoxin] + O2 + 2 H+ => (1S)-1,25-dihydroxy-24-oxocalciol + 2 oxidized [adrenodoxin] + 2 H2O
Rhea:RHEA:24974 1.14.15.16 (1S)-1,25-dihydroxy-24-oxocalciol + 2 oxidized [adrenodoxin] + 2 H2O => calcitetrol + 2 reduced [adrenodoxin] + O2 + 2 H+
Rhea:RHEA:24975 1.14.15.16 calcitetrol + 2 reduced [adrenodoxin] + O2 + 2 H+ <=> (1S)-1,25-dihydroxy-24-oxocalciol + 2 oxidized [adrenodoxin] + 2 H2O
Rhea:RHEA:49065 1.14.15.18 secalciferol + 2 reduced [adrenodoxin] + O2 + 2 H+ => calcitetrol + 2 oxidized [adrenodoxin] + H2O
Rhea:RHEA:49066 1.14.15.18 calcitetrol + 2 oxidized [adrenodoxin] + H2O => secalciferol + 2 reduced [adrenodoxin] + O2 + 2 H+
Rhea:RHEA:49067 1.14.15.18 secalciferol + 2 reduced [adrenodoxin] + O2 + 2 H+ <=> calcitetrol + 2 oxidized [adrenodoxin] + H2O
BioCyc:RXN-14052 1.14.15.16 CPD-10577 + 2 Reduced-adrenal-ferredoxins + 2 PROTON + OXYGEN-MOLECULE --> CPD-15059 + 2 Oxidized-adrenal-ferredoxins + 2 WATER
BioCyc:RXN-18233 1.14.15.18 CPD-13032 + 2 Reduced-adrenal-ferredoxins + 2 PROTON + OXYGEN-MOLECULE --> CPD-10577 + 2 Oxidized-adrenal-ferredoxins + WATER
BioCyc:RXN-9830 1.14.15.16 CALCITRIOL + 2 Reduced-adrenal-ferredoxins + OXYGEN-MOLECULE + 2 PROTON --> CPD-10577 + 2 Oxidized-adrenal-ferredoxins + WATER
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
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