5-Hydroxykynurenine (BioCAD00000004846)

feces

Metabolite Card

Formula: C10H12N2O4 (224.0797)
SMILES: NC(CC(=O)C1=C(N)C=CC(O)=C1)C(O)=O

Synonyms [en]

5-hydroxykynurenine; 5-Hydroxy-L-kynurenine; 2-Amino-4-(2-amino-5-hydroxyphenyl)-4-oxobutanoic acid; 5-hydroxykynurenine, (L)-isomer; 3-(2-amino-5-hydroxybenzoyl)alanine; 5-hydroxy-DL-kynurenine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

5-Hydroxykynurenine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004846). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

5-Hydroxykynurenine is found in the tryptophan metabolism pathway. It is created from 5-Hydroxy-N-formylkynurenine through the action of arylformamidase [EC:3.5.1.9]. 5-Hydroxykynurenine is then converted to 5-Hydroxykynurenamine by the action of dopa decarboxylase [EC:4.1.1.28].

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 720-00-3
  • PubChem: 440745
  • ChEBI: ChEBI:2076
  • ChEBI: ChEBI:36408
  • HMDB: HMDB0012819
  • KEGG: C05651
  • NCBI MeSH: 5-hydroxykynurenine
  • Wikipedia: 3-Hydroxykynurenine
  • Metlin: METLIN_63541
  • Coconut NaturalProduct: CNP0082980.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04909 4.1.1.28 5-hydroxykynurenamine decarboxy-lyase
KEGG:R04911 3.5.1.9 aryl-formylamine amidohydrolase
KEGG:R04913 2.6.1.- 5-hydroxykynurenine:2-oxoglutarate aminotransferase
View More
Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
WikiPathways:WP270 Tryptophan metabolism
PathBank:SMP0087330 Tryptophan Metabolism
PathBank:SMP0087237 Tryptophan Metabolism
PathBank:SMP0063693 Tryptophan Metabolism
PathBank:SMP0000063 Tryptophan Metabolism
PathBank:SMP0087451 Tryptophan Metabolism
View All Pathways