glutathione disulfide(2-) (BioCAD00000478513)

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Metabolite Card

Formula: C20H30N6O12S2 (610.1363)
SMILES: [NH3+][C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H]([NH3+])C([O-])=O)C(=O)NCC([O-])=O)C(=O)NCC([O-])=O)C([O-])=O

Synonyms [en]

glutathione disulfide; glutathione oxidized; (2S,2'S)-5,5'-[disulfanediylbis({(2R)-3-[(carboxylatomethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-azaniumyl-5-oxopentanoate); glutathione ox; glutathione disulfide dianion; oxidized glutathione

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

glutathione disulfide(2-). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000478513). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A doubly-charged peptide anion arising from deprotonation of the four carboxy groups and protonation of the two amino groups of glutathione disulfide; major species at pH 7.3." []

Entity Information

DBLinks

Other DBLinks
  • ChEBI: ChEBI:58297
  • BioCyc: OXIDIZED-GLUTATHIONE

Class / Ontology

Metabolic Network
ID EC Number Name
Rhea:RHEA:10721 1.5.4.1 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione
Rhea:RHEA:10722 1.5.4.1 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione => 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O
Rhea:RHEA:10723 1.5.4.1 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione
Rhea:RHEA:11465 1.8.4.1 L,L-homocystine + 2 glutathione => 2 L-homocysteine + glutathione disulfide
Rhea:RHEA:11466 1.8.4.1 2 L-homocysteine + glutathione disulfide => L,L-homocystine + 2 glutathione
Rhea:RHEA:11467 1.8.4.1 L,L-homocystine + 2 glutathione <=> 2 L-homocysteine + glutathione disulfide
Rhea:RHEA:11741 1.8.1.7 2 glutathione + NADP+ => glutathione disulfide + NADPH + H+
Rhea:RHEA:11742 1.8.1.7 glutathione disulfide + NADPH + H+ => 2 glutathione + NADP+
Rhea:RHEA:11743 1.8.1.7 2 glutathione + NADP+ <=> glutathione disulfide + NADPH + H+
Rhea:RHEA:12614 1.8.4.4 L-cystine + 2 glutathione => glutathione disulfide + 2 L-cysteine
Rhea:RHEA:12615 1.8.4.4 glutathione disulfide + 2 L-cysteine => L-cystine + 2 glutathione
Rhea:RHEA:12616 1.8.4.4 L-cystine + 2 glutathione <=> glutathione disulfide + 2 L-cysteine
Rhea:RHEA:13126 1.8.4.3 glutathione disulfide + CoA => CoA-glutathione + glutathione
Rhea:RHEA:13127 1.8.4.3 CoA-glutathione + glutathione => glutathione disulfide + CoA
Rhea:RHEA:13128 1.8.4.3 glutathione disulfide + CoA <=> CoA-glutathione + glutathione
Rhea:RHEA:14142 1.8.4.9 glutathione disulfide + sulfite + AMP + 2 H+ => adenosine 5'-phosphosulfate + 2 glutathione
Rhea:RHEA:14143 1.8.4.9 adenosine 5'-phosphosulfate + 2 glutathione => glutathione disulfide + sulfite + AMP + 2 H+
Rhea:RHEA:14144 1.8.4.9 glutathione disulfide + sulfite + AMP + 2 H+ <=> adenosine 5'-phosphosulfate + 2 glutathione
Rhea:RHEA:14506 2.8.1.3 thiosulfate + 2 glutathione => glutathione disulfide + hydrogen sulfide + sulfite + 2 H+
Rhea:RHEA:14507 2.8.1.3 glutathione disulfide + hydrogen sulfide + sulfite + 2 H+ => thiosulfate + 2 glutathione
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Organism Source

Taxonomy Source

Pathway Synthetic

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