8-oxo-dGTP(4-) (BioCAD00000476864)

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Metabolite Card

Formula: C10H12N5O14P3 (518.9594)
SMILES: Nc1nc2n([C@H]3C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)O3)c(=O)[nH]c2c(=O)[nH]1

Synonyms [en]

2'-deoxy-7,8-dihydro-8-oxo-guanosine 5'-triphosphate; 2'-deoxy-8-oxo-5'-O-({[(phosphonatooxy)phosphinato]oxy}phosphinato)-7,8-dihydroguanosine; 8-hydroxydeoxyguanosine 5'-triphosphate; 8-hydroxy-dGTP; 7,8-dihydro-8-oxo-2'-dGTP; 2'-deoxy-8-oxo-7,8-dihydroguanosine 5'-triphosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

8-oxo-dGTP(4-). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000476864). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A 2'-deoxyribonucleoside triphosphate oxoanion that is the tetraanion of 8-oxo-dGTP arising from deprotonation of the triphosphate OH groups. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []

Entity Information

DBLinks

Other DBLinks
  • PubChem: 135398564
  • ChEBI: ChEBI:77896
  • BioCyc: 8-hydroxy-dGTP
  • BioCyc: 8-Oxo-dGTP
  • NCBI MeSH: 8-hydroxy-2'-deoxyguanosine 5'-triphosphate

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:RXN-11410 DGTP + 2 CPD-12377 --> 8-Oxo-dGTP + WATER
BioCyc:RXN-11396 3.6.1.55 8-Oxo-dGTP + WATER --> PROTON + CPD-12365 + PPI
Rhea:RHEA:31576 3.6.1.55 8-oxo-dGTP + H2O => 8-oxo-dGMP + diphosphate + H+
Rhea:RHEA:31577 3.6.1.55 8-oxo-dGMP + diphosphate + H+ => 8-oxo-dGTP + H2O
Rhea:RHEA:31578 3.6.1.55 8-oxo-dGTP + H2O <=> 8-oxo-dGMP + diphosphate + H+
Rhea:RHEA:59981 3.6.1.69 8-oxo-dGTP + H2O => 8-oxo-dGDP + phosphate + H+
Rhea:RHEA:59982 3.6.1.69 8-oxo-dGDP + phosphate + H+ => 8-oxo-dGTP + H2O
Rhea:RHEA:59983 3.6.1.69 8-oxo-dGTP + H2O <=> 8-oxo-dGDP + phosphate + H+
Rhea:RHEA:64977 8-oxo-dGTP + 2 H2O => 8-oxo-dGMP + 2 phosphate + 2 H+
Rhea:RHEA:64978 8-oxo-dGMP + 2 phosphate + 2 H+ => 8-oxo-dGTP + 2 H2O
Rhea:RHEA:64979 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 phosphate + 2 H+
BioCyc:RXN-20666 3.6.1.69 8-Oxo-dGTP + WATER --> CPD-13853 + Pi + PROTON
BioCyc:RXN-14205 8-Oxo-dGTP + 2 WATER --> CPD-12365 + 2 Pi + 2 PROTON
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PlantCyc:SUGARBEET_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:TOMATO_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:AMBORELLA_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:BRAPA_FPSC_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:CACUMINATA_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:CANNUUM_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:CARROT_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:SETARIA_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:SPIDERFLOWER_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:SWITCHGRASS_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:TEA_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:MOSOBAMBOO_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:CZOFINGIENSIS_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:OBARTHII_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:OGLABERRIMA_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:OILPALM_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:FLAX_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:GRAPE_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:LJAPONICUS_PWY-6502 8-oxo-(d)GTP detoxification I
PlantCyc:MDOMESTICA_PWY-6502 oxidized GTP and dGTP detoxification
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