4-Imidazolone-5-propanoate (BioCAD00000004419)

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Metabolite Card

Formula: C6H8N2O3 (156.0535)
SMILES: OC(=O)CCC1N=CNC1=O

Synonyms [en]

4-imidazolone-5-propanoate; 4-Imidazolone-5-propionic acid; Imidazol-4-one-5-propionic acid; 4,5-Dihydro-4-oxo-5-imidazolepropanoate; 3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid; imidazol-4-one-5-propionate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

4-Imidazolone-5-propanoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004419). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

4-Imidazolone-5-propanoate is a metabolite of histidine metabolism. It is produced from urocanic acid by the enzyme urocanate hydratase [EC:4.2.1.49]. 4-Imidazolone-5-propionic acid can spontaneously decay to 4-oxoglutaramate or formylisoglutamine. It is also converted to N-forminimo-L-glutamate by the enzyme imidazolonepropionase [EC:3.5.2.7].

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 17340-16-8
  • CAS Registry Number: 36117-26-7
  • PubChem: 128
  • PubChem: 25243959
  • ChEBI: ChEBI:27384
  • HMDB: HMDB0001014
  • KEGG: C03680
  • Wikipedia: Imidazol-4-one-5-propionic acid
  • RefMet: RM0156344
  • Metlin: METLIN_319
  • Coconut NaturalProduct: CNP0515436.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00069 1.14.13.- 4-imidazolone-5-propanoate:oxygen oxidoreductase
KEGG:R02288 3.5.2.7 4-imidazolone-5-propanoate amidohydrolase
KEGG:R02914 4.2.1.49 4,5-dihydro-4-oxo-5-imidazolepropanoate hydro-lyase
KEGG:R04282 C03680 + C00001<=>C16674
KEGG:R04283 C03680 + C00001<=>C05572 + C00058 + C00014
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Organism Source

Taxonomy Source

  1. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
WikiPathways:WP3604 Biochemical pathways: part I
WikiPathways:WP4661 Amino acid metabolism pathway excerpt: histidine catabolism extension
PathBank:SMP0087314 Histidine Metabolism
PathBank:SMP0120713 Histidinemia
PathBank:SMP0120493 Histidinemia
PathBank:SMP0000044 Histidine Metabolism
PathBank:SMP0000191 Histidinemia
PathBank:SMP0087219 Histidine Metabolism
PathBank:SMP0063632 Histidine Metabolism
View All Pathways