Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol (BioCAD00000024767)

{$topic}

Metabolite Card

Formula: C47H82N2O22P2 (1088.4834)
SMILES: OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(=O)C)[C@@H](O[C@@H]2CO)O[C@H]2[C@H](O)[C@@H](NC(=O)C)[C@H](O[C@@H]2CO)OP(=O)(O)OP(=O)(O)OCCC(C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)[C@@H](O)[C@@H](O)[C@@H]1O

Synonyms [en]

Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol; b-(1->4)-D-mannosylchitobiosyldiphosphodolichol; beta-(1->4)-delta-mannosylchitobiosyldiphosphodolichol; beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol; Man-beta1->4glcnac-beta1->4glcnac-PP-dol; [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-acetamido-5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2~{S},3~{S},4~{S},5~{S},6~{R})-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [hydroxy-[(6~{E},10~{E},14~{E})-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraenoxy]phosphoryl] hydrogen phosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000024767). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol is a lipid-linked oligosaccharide. It is part of the N-glycan biosynthesis pathway. Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol is formed by chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) via the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol. It is also a reactant or product of glycolipid 3-alpha-mannosyltransferase or mannosyltransferase II. This enzyme transfers an alpha-D-mannosyl residue from GDP-mannose to a lipid-linked (dolichol) oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • PubChem: 45259170
  • ChEBI: ChEBI:18396
  • HMDB: HMDB0011673
  • HMDB: HMDB11673
  • KEGG: C05860
  • Metlin: METLIN_62413
  • Coconut NaturalProduct: CNP0083579.1

Class / Ontology

Metabolic Network
ID EC Number Name
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-CEL-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-CFA-597592 Post-translational protein modification
Reactome:R-DRE-392499 Metabolism of proteins
Reactome:R-DDI-597592 Post-translational protein modification
Reactome:R-DDI-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-GGA-597592 Post-translational protein modification
Reactome:R-GGA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-1643685 Disease
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-SCE-597592 Post-translational protein modification
Reactome:R-SPO-446203 Asparagine N-linked glycosylation
Reactome:R-SSC-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-XTR-446203 Asparagine N-linked glycosylation
Reactome:R-CEL-392499 Metabolism of proteins
Reactome:R-CEL-597592 Post-translational protein modification
Reactome:R-CEL-446203 Asparagine N-linked glycosylation
View All Pathways