1D-myo-Inositol 1,3,4,5,6-pentakisphosphate (BioCAD00000002195)

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Metabolite Card

Formula: C6H17O21P5 (579.895)
SMILES: O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O

Synonyms [en]

1D-myo-Inositol 1,3,4,5,6-pentakisphosphate; inositol 1,3,4,5,6-pentakisphosphate; D-myo-Inositol 1,3,4,5,6-pentakisphosphate; myo-inositol 1,3,4,5,6-pentakisphosphate; inositol pentaphosphate; myo-Inositol pentakisphosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

1D-myo-Inositol 1,3,4,5,6-pentakisphosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000002195). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

myo-Inositol 1,3,4,5,6-pentakisphosphate, also known as Ins(1,3,4,5,6)P5 or inositol pentaphosphate, is an inositol polyphosphate of emerging significance in cellular signalling. Both Ins(1,3,4,5,6)P5 and its C-2 epimer scyllo-inositol pentakisphosphate (scyllo-InsP(5)) were synthesized from the same myo-inositol-based precursor (PMID: 16755629). InsP6, Ins(1,3,4,5,6)P5, and their close metabolic relatives are amongst the more abundant intracellular inositol polyphosphates. They are involved in chromatin organization, DNA maintenance, gene transcription, nuclear mRNA transport, membrane trafficking, and control of cell proliferation (PMID: 14992690).

Cytoplasm Nucleus
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 20298-95-7
  • CAS Registry Number: 20298-96-8
  • CAS Registry Number: 20298-97-9
  • CAS Registry Number: 26326-85-2
  • CAS Registry Number: NA
  • PubChem: 439468
  • ChEBI: ChEBI:11369
  • ChEBI: ChEBI:16322
  • HMDB: HMDB0003529
  • KEGG: C01284
  • NCBI MeSH: inositol pentaphosphate
  • Wikipedia: Inositol_pentakisphosphate
  • RefMet: RM0156094
  • Metlin: METLIN_44862
  • Coconut NaturalProduct: CNP0283371.1
  • Coconut NaturalProduct: CNP0283371.2
  • Coconut NaturalProduct: CNP0283371.3
  • Coconut NaturalProduct: CNP0283371.4

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R03478 2.7.1.140 ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase
KEGG:R03479 2.7.1.134 ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase
KEGG:R05202 2.7.1.158 ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase
KEGG:R05801 2.7.1.151 ATP:1D-myo-inositol-1,4,5,6-tetrakisphosphate 3-phosphotransferase
KEGG:R10065 2.7.1.151 ATP:1D-myo-inositol-1,4,5-trisphosphate 3,6-phosphotransferase
KEGG:R10953 2.7.1.151 ATP:1D-myo-inositol-1,3,4,5-tetrakisphosphate 6-phosphotransferase
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Organism Source

Taxonomy Source

  1. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY-6369 inositol pyrophosphates biosynthesis
BioCyc:HUMAN_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
BioCyc:META_PWY-4661 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)
BioCyc:ARA_PWY-4562 lipid-dependent phytate biosynthesis II (via Ins(1,3,4)P3)
BioCyc:ARA_PWY-4541 lipid-dependent phytate biosynthesis I (via Ins(1,4,5)P3)
BioCyc:HUMAN_PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis
BioCyc:META_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
BioCyc:META_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
BioCyc:META_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:META_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
BioCyc:YEAST_PWY3O-402 inositol phosphate biosynthesis
BioCyc:ARA_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
BioCyc:ARA_PWY-6369 inositol pyrophosphates biosynthesis
BioCyc:ARA_PWY-4765 superpathway of lipid-dependent phytate biosynthesis
BioCyc:HUMAN_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
BioCyc:HUMAN_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
BioCyc:META_PWY-6361 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
BioCyc:META_PWY-6372 1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)
BioCyc:META_PWY-6369 inositol diphosphates biosynthesis
BioCyc:YEAST_PWY-6369 inositol pyrophosphates biosynthesis
View All Pathways