CDP-DG(18:0/18:0) (BioCAD00000020858)

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Metabolite Card

Formula: C48H89N3O15P2 (1009.5769)
SMILES: [H][C@@](COC(=O)CCCCCCCCCCCCCCCCC)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1O)N1C=CC(N)=NC1=O)OC(=O)CCCCCCCCCCCCCCCCC

Synonyms [en]

CDP-DG(18:0/18:0); CDP-DG(36:0); CDP-Diacylglycerol(36:0); CDP-Diacylglycerol(18:0/18:0); 1,2-dioctadecanoyl-sn-glycero-3-cytidine 5'-diphosphate; 2-distearoyl-rac-glycero-3-cytidine-5'-diphosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

CDP-DG(18:0/18:0). 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000020858). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

CDP-DG(18:0/18:0) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol. CDP-diacylglycerol (CDP-DG) is an important branchpoint intermediate in eukaryotic phospholipid biosynthesis and could be a key regulatory molecule in phospholipid metabolism. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. CDP-DG(18:0/18:0), in particular, consists of one chain of stearic acid at the C-1 position and one chain of stearic acid at the C-2 position. The stearic acid moiety is derived from animal fats, coco butter and sesame oil, while the stearic acid moiety is derived from animal fats, coco butter and sesame oil. CDP-diacylglycerols are intermediates in the synthesis of phosphatidylglycerols (PG, PC, PS, PI), which is catalyzed by CDP-diacyl synthase, synthase, phosphatidylglycerolphosphate (PGP) synthase, phosphatidylinositol (PI) synthase, and phosphatidylserine (PS) synthase. Cytidine diphosphate diacylglycerols are rarely noticed in analyses of lipid compositions of tissues, as they are present is such small amounts, perhaps only 0.05% or so of the total phospholipids.

Entity Information

DBLinks

Other DBLinks
  • PubChem: 53477922
  • ChEBI: ChEBI:104121
  • HMDB: HMDB0006978
  • HMDB: HMDB06978
  • LipidMaps: LMGP13010013
  • BioCyc: CPD-12814
  • Metlin: METLIN_58613
  • Coconut NaturalProduct: CNP0082130.1
  • Coconut NaturalProduct: CNP0082130.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PathBank:SMP0001787 phospholipid biosynthesis (PE(18:0/18:0))
PathBank:SMP0027075 Cardiolipin Biosynthesis CL(16:0/16:1(9Z)/18:0/18:0)
PathBank:SMP0027115 Cardiolipin Biosynthesis CL(16:0/18:0/18:0/18:0)
PathBank:SMP0028011 Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/16:1(9Z))
PathBank:SMP0028015 Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/18:2(9Z,12Z))
PathBank:SMP0028019 Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
PathBank:SMP0028023 Cardiolipin Biosynthesis CL(18:0/18:0/18:0/18:1(9Z))
PathBank:SMP0028027 Cardiolipin Biosynthesis CL(18:0/18:0/18:0/22:5(7Z,10Z,13Z,16Z,19Z))
PathBank:SMP0028031 Cardiolipin Biosynthesis CL(18:0/18:0/18:1(11Z)/18:0)
PathBank:SMP0028035 Cardiolipin Biosynthesis CL(18:0/18:0/18:1(11Z)/20:4(5Z,8Z,11Z,14Z))
PathBank:SMP0028039 Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/16:0)
PathBank:SMP0028043 Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/18:1(9Z))
PathBank:SMP0028047 Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z))
PathBank:SMP0028051 Cardiolipin Biosynthesis CL(18:0/18:0/18:2(9Z,12Z)/18:0)
PathBank:SMP0028055 Cardiolipin Biosynthesis CL(18:0/18:0/18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z))
PathBank:SMP0028059 Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/16:0)
PathBank:SMP0028063 Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/18:1(9Z))
PathBank:SMP0028067 Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/22:5(7Z,10Z,13Z,16Z,19Z))
PathBank:SMP0028071 Cardiolipin Biosynthesis CL(18:0/18:0/22:5(4Z,7Z,10Z,13Z,16Z)/18:0)
PathBank:SMP0028075 Cardiolipin Biosynthesis CL(18:0/18:0/22:5(4Z,7Z,10Z,13Z,16Z)/20:4(5Z,8Z,11Z,14Z))
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