CDP-DG(18:0/18:0) (BioCAD00000020858)
Metabolite Card
Formula: C48H89N3O15P2 (1009.5769)
SMILES: [H][C@@](COC(=O)CCCCCCCCCCCCCCCCC)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1O)N1C=CC(N)=NC1=O)OC(=O)CCCCCCCCCCCCCCCCC
Synonyms [en]
CDP-DG(18:0/18:0); CDP-DG(36:0); CDP-Diacylglycerol(36:0); CDP-Diacylglycerol(18:0/18:0); 1,2-dioctadecanoyl-sn-glycero-3-cytidine 5'-diphosphate; 2-distearoyl-rac-glycero-3-cytidine-5'-diphosphate
Last reviewed on 2024-06-28.
Cite this Page
CDP-DG(18:0/18:0). 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000020858). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
CDP-DG(18:0/18:0) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol. CDP-diacylglycerol (CDP-DG) is an important branchpoint intermediate in eukaryotic phospholipid biosynthesis and could be a key regulatory molecule in phospholipid metabolism. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. CDP-DG(18:0/18:0), in particular, consists of one chain of stearic acid at the C-1 position and one chain of stearic acid at the C-2 position. The stearic acid moiety is derived from animal fats, coco butter and sesame oil, while the stearic acid moiety is derived from animal fats, coco butter and sesame oil. CDP-diacylglycerols are intermediates in the synthesis of phosphatidylglycerols (PG, PC, PS, PI), which is catalyzed by CDP-diacyl synthase, synthase, phosphatidylglycerolphosphate (PGP) synthase, phosphatidylinositol (PI) synthase, and phosphatidylserine (PS) synthase. Cytidine diphosphate diacylglycerols are rarely noticed in analyses of lipid compositions of tissues, as they are present is such small amounts, perhaps only 0.05% or so of the total phospholipids.
DBLinks
- CAS Registry Number:
- PubChem CID: 53477922
- ChEBI: 104121
- HMDB: HMDB0006978
- LipidMaps: LMGP13010013
- KEGG:
- BioCyc: CPD-12814
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- PubChem: 53477922
- ChEBI: ChEBI:104121
- HMDB: HMDB0006978
- HMDB: HMDB06978
- LipidMaps: LMGP13010013
- BioCyc: CPD-12814
- Metlin: METLIN_58613
- Coconut NaturalProduct: CNP0082130.1
- Coconut NaturalProduct: CNP0082130.2
Class / Ontology
- WishartLab ClassyFire: [CDP-glycerols] CDP-glycerols
- LipidMaps: [CDP-diacylglycerols [GP1301]] CDP-diacylglycerols [GP1301]
- ChEBI: [CHEBI:104121] 1,2-dioctadecanoyl-sn-glycero-3-cytidine 5'-diphosphate
- Coconut NaturalProduct: [CDP-Glycerols] CDP-Glycerols
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0001787 | phospholipid biosynthesis (PE(18:0/18:0)) |
| PathBank:SMP0027075 | Cardiolipin Biosynthesis CL(16:0/16:1(9Z)/18:0/18:0) |
| PathBank:SMP0027115 | Cardiolipin Biosynthesis CL(16:0/18:0/18:0/18:0) |
| PathBank:SMP0028011 | Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/16:1(9Z)) |
| PathBank:SMP0028015 | Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/18:2(9Z,12Z)) |
| PathBank:SMP0028019 | Cardiolipin Biosynthesis CL(18:0/18:0/16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) |
| PathBank:SMP0028023 | Cardiolipin Biosynthesis CL(18:0/18:0/18:0/18:1(9Z)) |
| PathBank:SMP0028027 | Cardiolipin Biosynthesis CL(18:0/18:0/18:0/22:5(7Z,10Z,13Z,16Z,19Z)) |
| PathBank:SMP0028031 | Cardiolipin Biosynthesis CL(18:0/18:0/18:1(11Z)/18:0) |
| PathBank:SMP0028035 | Cardiolipin Biosynthesis CL(18:0/18:0/18:1(11Z)/20:4(5Z,8Z,11Z,14Z)) |
| PathBank:SMP0028039 | Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/16:0) |
| PathBank:SMP0028043 | Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/18:1(9Z)) |
| PathBank:SMP0028047 | Cardiolipin Biosynthesis CL(18:0/18:0/18:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z)) |
| PathBank:SMP0028051 | Cardiolipin Biosynthesis CL(18:0/18:0/18:2(9Z,12Z)/18:0) |
| PathBank:SMP0028055 | Cardiolipin Biosynthesis CL(18:0/18:0/18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) |
| PathBank:SMP0028059 | Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/16:0) |
| PathBank:SMP0028063 | Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/18:1(9Z)) |
| PathBank:SMP0028067 | Cardiolipin Biosynthesis CL(18:0/18:0/20:4(5Z,8Z,11Z,14Z)/22:5(7Z,10Z,13Z,16Z,19Z)) |
| PathBank:SMP0028071 | Cardiolipin Biosynthesis CL(18:0/18:0/22:5(4Z,7Z,10Z,13Z,16Z)/18:0) |
| PathBank:SMP0028075 | Cardiolipin Biosynthesis CL(18:0/18:0/22:5(4Z,7Z,10Z,13Z,16Z)/20:4(5Z,8Z,11Z,14Z)) |