trans-3-Decenoyl-CoA (BioCAD00000020081)

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Metabolite Card

Formula: C31H52N7O17P3S (919.2353)
SMILES: CCCCCC\C=C\CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12

Synonyms [en]

trans-3-decenoyl-CoA; 3-trans-decenoyl-CoA; 3-trans-decenoyl-coenzyme A; (e)-S-3-Decenoate; S-(3E)-3-Decenoic acid; trans-dec-3-enoyl-CoA

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

trans-3-Decenoyl-CoA. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000020081). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

trans-3-Decenoyl-CoA is an intermediate in fatty acid metabolism. trans-3-Decenoyl-CoA is the substrate of medium-chain acyl-CoA dehydrogenase (MCAD, EC 1.3.99.3) MCAD acts on C4-C16 acyl-CoAs with its peak activity toward medium-chain (C6-C12) substrates. MCAD is a key enzyme for the beta-oxidation of fatty acids. MCAD deficiency is caused by mutation in the medium-chain acyl-CoA dehydrogenase gene (ACADM; OMIM 607008). Inherited deficiency of medium-chain acyl-CoA dehydrogenase is characterized by intolerance to prolonged fasting, recurrent episodes of hypoglycemic coma with medium-chain dicarboxylic aciduria, impaired ketogenesis, and low plasma and tissue carnitine levels. The disorder may be severe, and even fatal, in young patients. It has been reported that between 19 and 25% of patients with undiagnosed deficiency of MCAD die during their first episode of metabolic decompensation. (PMID: 15850406).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 6410-54-4
  • PubChem: 16019966
  • ChEBI: ChEBI:29126
  • HMDB: HMDB0002137
  • HMDB: HMDB02137
  • LipidMaps: LMFA07050386
  • RefMet: RM0153966
  • Metlin: METLIN_6504
  • Coconut NaturalProduct: CNP0002355.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-556833 Metabolism of lipids
Reactome:R-BTA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-CEL-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-CFA-1430728 Metabolism
Reactome:R-CFA-556833 Metabolism of lipids
Reactome:R-CFA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-GGA-8978868 Fatty acid metabolism
Reactome:R-GGA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-HSA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-XTR-8978868 Fatty acid metabolism
Reactome:R-XTR-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Reactome:R-BTA-8978868 Fatty acid metabolism
Reactome:R-BTA-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-CEL-556833 Metabolism of lipids
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