3-Pyridylacetic acid (BioCAD00000019963)

blood

Metabolite Card

Formula: C7H7NO2 (137.0477)
SMILES: OC(=O)CC1=CN=CC=C1

Synonyms [en]

3-pyridylacetic acid; a-(3-Pyridyl)acetate; 2-(pyridin-3-yl)acetic acid; minedil; 2-(3-pyridyl)acetic acid; coletin

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Pyridylacetic acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019963). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

3-Pyridylacetic acid is a breakdown product of nicotine (and other tobacco alkaloids) and is part of the nicotine degradation pathway. It is formed from 4-(3-pyridyl)-butanoate. One alkaloid in particular, myosmine, appears to be a major source for 3-pyridylacetic acid. The alkaloid myosmine is present not only in tobacco products but also in various foods. Myosmine is easily nitrosated, yielding 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and the esophageal tobacco carcinogen N'-nitrosonornicotine. The two major metabolites of myosmine metabolism have been identified as 3-pyridylacetic acid (20-26%) and 4-oxo-4-(3-pyridyl)butyric acid (50-60%) (PMID:16079272). 3-pyridylacetatic acid is an analog of nicotinic acid. (PMID 13898750).

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 501-81-5
  • CAS Registry Number: 6419-36-9
  • CAS Registry Number: NA
  • PubChem: 108
  • ChEBI: ChEBI:86390
  • HMDB: HMDB0001538
  • HMDB: HMDB01538
  • NCBI MeSH: 2-(3-pyridine)acetic acid
  • RefMet: RM0108069
  • MoNA: GLS00151
  • MoNA: HMDB0001538_ms_ms_1634
  • MoNA: HMDB0001538_ms_ms_1635
  • MoNA: HMDB0001538_ms_ms_1636
  • MoNA: MoNA010771
  • MoNA: MoNA010772
  • MoNA: MoNA010773
  • MoNA: MoNA010774
  • MoNA: MoNA010775
  • MoNA: MoNA010776
  • MoNA: OUF00059
  • Metlin: METLIN_6308
  • Coconut NaturalProduct: CNP0105682.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

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