Suberylglycine (BioCAD00000019873)

blood urine

Metabolite Card

Formula: C10H17NO5 (231.1107)
SMILES: OC(=O)CCCCCCC(=O)NCC(O)=O

Synonyms [en]

Suberylglycine; Suberylglycin; 7-[(carboxymethyl)carbamoyl]heptanoic acid; suberyl glycine; 8-(carboxymethylamino)-8-oxooctanoic acid; Octanoic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Suberylglycine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019873). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Suberylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycineSuberylglycine is a dicarboxylic acid. It is formed by glycine-N-acylase catalyzed conjugation (PMID 947635). It can be used for the diagnosis of hereditary medium-chain acyl-CoA dehydrogenase deficiency (PMID 2775902). Suberylglycine is found to be associated with propionic acidemia, which is an inborn error of metabolism.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 60317-54-6
  • PubChem: 6453952
  • ChEBI: ChEBI:88811
  • HMDB: HMDB0000953
  • HMDB: HMDB00953
  • NCBI MeSH: suberylglycine
  • RefMet: RM0031731
  • MoNA: HMDB0000953_ms_ms_1345
  • MoNA: HMDB0000953_ms_ms_1346
  • MoNA: HMDB0000953_ms_ms_1347
  • MoNA: MoNA033308
  • MoNA: MoNA033309
  • MoNA: MoNA033310
  • MoNA: MoNA035468
  • MoNA: MoNA035469
  • MoNA: MoNA035471
  • MoNA: MoNA036800
  • MoNA: MoNA036801
  • MoNA: MoNA036802
  • MoNA: MoNA036803
  • MoNA: MoNA036805
  • MoNA: MoNA036806
  • MoNA: MoNA037591
  • MoNA: MoNA038337
  • MoNA: MoNA038832
  • MoNA: MoNA038835
  • Metlin: METLIN_5899
  • Coconut NaturalProduct: CNP0346714.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

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