Succinyladenosine (BioCAD00000019864)

blood cerebrospinal fluid (csf) urine placenta

Metabolite Card

Formula: C14H17N5O8 (383.1077)
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N[C@@H](CC(O)=O)C(O)=O)N=CN=C12

Synonyms [en]

Succinoadenosine; Succinyladenosine; N-(9-beta-D-ribofuranosyl-9H-purin-6-yl)-L-aspartic acid; N-9-ribofuranosyl-9H-purin-6-yl-Aspartic acid; (S)-N-(1,2-dicarboxyethyl)-Adenosine; 6-(1,2-Dicarboxyethylamino)-9-beta-D-ribofuranosylpurine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Succinyladenosine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019864). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Succinyladenosine (SAdo) is one of the dephosphorylated enzyme substrate that accumulates in body fluids of patients with adenylosuccinate lyase (ADSL) deficiency, the other being 5-amino-4-imidazole-N-succinocarboxamide riboside (SAICAr). ADSL is an inherited metabolic disease characterized by various degrees of psychomotor retardation (PMID 15902552). The severity of the clinical presentation correlates with a low S-Ado/SAICAr ratio in body fluids (PMID: 15571235). Normally Succinyladenosine is not found in blood or CSF but may be detected in trace amounts in urine (OMIM 103050). Succinyladenosine is also found to be associated with fumarase deficiency, another inborn error of metabolism.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 4542-23-8
  • PubChem: 163341915
  • PubChem: 165243
  • PubChem: 20849086
  • ChEBI: ChEBI:183825
  • ChEBI: ChEBI:71169
  • HMDB: HMDB0000912
  • HMDB: HMDB00912
  • NCBI MeSH: succinyladenosine
  • RefMet: RM0136023
  • MoNA: MoNA017954
  • Metlin: METLIN_5867
  • Coconut NaturalProduct: CNP0105148.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
WikiPathways:WP4792 Purine metabolism
WikiPathways:WP4224 Purine metabolism and related disorders
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