Metabolite Card
Formula: C7H7NO4 (169.0375)
SMILES: OC(=O)CNC(=O)C1=CC=CO1
Synonyms [en]
2-Furoylglycine; N-(2-FUROYL)GLYCINE; Furoylglycine; N-(carboxymethyl)-2-Furancarboxamide; Pyromucurate; N-(2-Furanylcarbonyl)glycine
Last reviewed on 2024-06-28.
Cite this Page
2-Furoylglycine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000019675). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
2-Furoylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:. acyl-CoA + glycine < -- > CoA + N-acylglycine. Dietary studies show that 2-Furoylglycine precursors are of exogenous origin. Most probably from furan derivatives found in food prepared by strong heating. This may explain the absence of 2-furoylglycine in urine of breastfed children (PMID 4630229). 2-Furoylglycine is also a microbial metabolite.
DBLinks
- CAS Registry Number: 5657-19-2
- PubChem CID: 21863
- ChEBI: 82912
- HMDB: HMDB0000439
- LipidMaps:
- KEGG:
- BioCyc:
- NCBI MeSH: furoylglycine
- Wikipedia:
Other DBLinks
- CAS Registry Number: 5657-19-2
- CAS Registry Number: NA
- PubChem: 21863
- ChEBI: ChEBI:82912
- HMDB: HMDB0000439
- HMDB: HMDB00439
- NCBI MeSH: furoylglycine
- RefMet: RM0157457
- MoNA: FiehnHILIC000546
- MoNA: FiehnHILIC001343
- MoNA: FiehnHILIC002120
- MoNA: FiehnHILIC002835
- MoNA: HMDB0000439_ms_ms_638
- MoNA: HMDB0000439_ms_ms_639
- MoNA: HMDB0000439_ms_ms_640
- MoNA: MoNA010815
- MoNA: MoNA010816
- MoNA: MoNA010817
- MoNA: MoNA010818
- MoNA: MoNA035562
- MoNA: MoNA035563
- MoNA: MoNA035565
- MoNA: MoNA038375
- MoNA: NUTRI-METAB-FEM-NEG000875
- MoNA: NUTRI-METAB-FEM-NEG000876
- MoNA: NUTRI-METAB-FEM-NEG000877
- MoNA: NUTRI-METAB-FEM-NEG000878
- MoNA: NUTRI-METAB-FEM-NEG000879
- MoNA: NUTRI-METAB-FEM-NEG000880
- MoNA: NUTRI-METAB-FEM-NEG000881
- MoNA: NUTRI-METAB-FEM-NEG000882
- MoNA: NUTRI-METAB-FEM-NEG000883
- MoNA: NUTRI-METAB-FEM-NEG000884
- MoNA: NUTRI-METAB-FEM-NEG000885
- MoNA: NUTRI-METAB-FEM-NEG000886
- MoNA: NUTRI-METAB-FEM-NEG000887
- MoNA: NUTRI-METAB-FEM-NEG000888
- MoNA: NUTRI-METAB-FEM-NEG000889
- MoNA: NUTRI-METAB-FEM-NEG000890
- MoNA: NUTRI-METAB-FEM-NEG000891
- MoNA: NUTRI-METAB-FEM-NEG001148
- MoNA: NUTRI-METAB-FEM-NEG001149
- MoNA: NUTRI-METAB-FEM-NEG001150
- MoNA: NUTRI-METAB-FEM-NEG001151
- MoNA: VF-NPL-LTQ000452
- Metlin: METLIN_5428
- Coconut NaturalProduct: CNP0131505.0
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:82912] N-(2-furoyl)glycine
- Coconut NaturalProduct: [Aminoacids] Aminoacids