3-Hydroxytetradecanedioic acid (BioCAD00000019643)

blood urine

Metabolite Card

Formula: C14H26O5 (274.178)
SMILES: OC(CCCCCCCCCCC(O)=O)CC(O)=O

Synonyms [en]

3-Hydroxytetradecanedioic acid; 3-Hydroxytetradecanedioate; 3-HYDROXY-TETRADECANEDIOIC ACID; 73179-89-2; Q27161462; Tetradecanedioic acid,3-hydroxy-

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Hydroxytetradecanedioic acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019643). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

3-Hydroxytetradecanedioic acid is an unusual 3-hydroxydicarboxylic acid human metabolite found occasionally in urine. (PMID 2925825) High levels of 3-Hydroxytetradecanedioic acid (and other 3-hydroxydicarboxylic acids) were detected in the urine of a patient with 3-hydroxydicarboxylic aciduria (PMID 1507493), due to acute intoxication associated with hopantenate occurs owing to pantothenic acid deficiency or the inhibition of CoA-requiring reactions during stress, i.e., infection, prolonged fasting, or malnutrition (PMID 2026687), and in a patient with thanatophoric dysplasia due to enhanced but incomplete oxidation of fatty acid, a consequence of a heterozygous point mutation, S249C in the fibroblast growth factor receptor 3 gene. (PMID 11879084).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 73179-89-2
  • PubChem: 20848956
  • ChEBI: ChEBI:89276
  • HMDB: HMDB0000394
  • HMDB: HMDB00394
  • LipidMaps: LMFA01170094
  • RefMet: RM0153707
  • Metlin: METLIN_5383
  • Metlin: METLIN_74937
  • Coconut NaturalProduct: CNP0240170.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

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