12-Hydroxydodecanoic acid (BioCAD00000001873)

plant natural products microbial natural products

Metabolite Card

Formula: C12H24O3 (216.1725)
SMILES: OCCCCCCCCCCCC(O)=O

Synonyms [en]

12-hydroxydodecanoic acid; omega-Hydroxydodecanoic acid; 12-hydroxy lauric acid; Sabinic acid; omega-OH dodecanoic acid; omega-hydroxydodecanoate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

12-Hydroxydodecanoic acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000001873). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

12-hydroxydodecanoic acid is the substrate of the human glutathione-dependent formaldehyde dehydrogenase (EC1.1.1.1). The enzyme that catalyzes the conversion of alcohols to aldehydes is a zinc-containing dimeric enzyme responsible for the oxidation of long-chain alcohols and omega-hydroxy fatty acids. (OMIM). The human glutathione-dependent formaldehyde dehydrogenase is unique among the structurally studied members of the alcohol dehydrogenase family in that it follows a random bi kinetic mechanism forming a binary complex, and a ternary complex with NAD+. (PMID 12196016).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 27925-01-5
  • CAS Registry Number: 505-95-3
  • PubChem: 79034
  • ChEBI: ChEBI:39567
  • HMDB: HMDB0002059
  • HMDB: HMDB02059
  • LipidMaps: LMFA01050039
  • KEGG: C08317
  • NCBI MeSH: 12-hydroxydodecanoic acid
  • DrugBank: DB03704
  • RefMet: RM0153180
  • MoNA: BAF_UVA_POS000285
  • MoNA: BAF_UVA_POS000286
  • MoNA: BAF_UVA_POS000287
  • MoNA: BAF_UVA_POS000826
  • MoNA: CCMSLIB00005463886
  • MoNA: CCMSLIB00005463887
  • MoNA: CCMSLIB00005463888
  • MoNA: CCMSLIB00005463889
  • MoNA: CCMSLIB00005720892
  • MoNA: HMDB0002059_c_ms_99748
  • MoNA: HMDB0002059_c_ms_99749
  • MoNA: HMDB0002059_ms_ms_1974
  • MoNA: JP011923
  • MoNA: JP011924
  • MoNA: MoNA016920
  • MoNA: MoNA032544
  • MoNA: MoNA032546
  • MoNA: MoNA032547
  • MoNA: MoNA034669
  • MoNA: MoNA034670
  • MoNA: MoNA034674
  • MoNA: MoNA037344
  • MoNA: MoNA038096
  • Metlin: METLIN_6465
  • Coconut NaturalProduct: CNP0273728.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Acremonium furcatum [ncbi taxid: ]
  2. Boykinia tellimoides [ncbi taxid: ]
  3. Chamonixia caespitosa [ncbi taxid: 90414]
  4. Cucumaria frondosa [ncbi taxid: 36326]
  5. Cupressus sempervirens [ncbi taxid: 13469]
  6. Juniperus oxycedrus [ncbi taxid: 69008]
  7. Pinus radiata [ncbi taxid: 3347]
  8. Pterocarpus dalbergioides [ncbi taxid: 1071182]
  9. Tetradenia riparia [ncbi taxid: 992795]
  10. Thalictrum sachalinense [ncbi taxid: 1264570]

Pathway Synthetic

pathway id name
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-211945 Phase I - Functionalization of compounds
Reactome:R-CFA-1430728 Metabolism
Reactome:R-DRE-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-DME-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-DME-211935 Fatty acids
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-211935 Fatty acids
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-211935 Fatty acids
Reactome:R-RNO-211945 Phase I - Functionalization of compounds
Reactome:R-SSC-211945 Phase I - Functionalization of compounds
Reactome:R-XTR-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-BTA-211935 Fatty acids
Reactome:R-CFA-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-DRE-211945 Phase I - Functionalization of compounds
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-211945 Phase I - Functionalization of compounds
View All Pathways