trans-3-Hydroxycinnamate (BioCAD00000018689)

blood feces urine

Metabolite Card

Formula: C9H8O3 (164.0473)
SMILES: OC(=O)\C=C\C1=CC(O)=CC=C1

Synonyms [en]

m-coumaric acid; m-Hydroxycinnamic acid; trans-3-Hydroxycinnamate; (E)-3-(3-Hydroxyphenyl)-2-propenoic acid; 3-(3-hydroxyphenyl)-2-propenoic acid; 3-(3-hydroxyphenyl)prop-2-enoic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

trans-3-Hydroxycinnamate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000018689). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

m-Coumaric acid, also known as 3-coumarate, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. m-Coumaric acid exists in all living organisms, ranging from bacteria to humans. m-Coumaric acid (CAS: 588-30-7) is a polyphenol metabolite from caffeic acid, formed by the gut microflora. Outside of the human body, m-Coumaric acid is found, on average, in the highest concentration within a few different foods, such as olives, corns, and beers. m-Coumaric acid has also been detected, but not quantified in several different foods, such as carrots, strawberries, grape wines, garden tomato, and bilberries. MCT-mediated absorption of phenolic compounds per se and their colonic metabolites would exert a significant impact on human health (PMID:16870009, 15479001, 15479001). m-Coumaric acid is transported by the monocarboxylic acid transporter (MCT). The amount of this compound in human biofluids is diet-dependant. m-Coumaric acid is detected after the consumption of whole grain.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 14755-02-3
  • CAS Registry Number: 588-30-7
  • PubChem: 11496
  • PubChem: 637541
  • ChEBI: ChEBI:32357
  • HMDB: HMDB0001713
  • KEGG: C12621
  • NCBI MeSH: 3-coumaric acid
  • Wikipedia: M-Coumaric_acid
  • RefMet: RM0136110
  • MoNA: FiehnHILIC002809
  • MoNA: FiehnLib000236
  • MoNA: HMDB0001713_c_ms_1588
  • MoNA: HMDB0001713_ms_ms_1675
  • MoNA: HMDB0001713_ms_ms_1676
  • MoNA: HMDB0001713_ms_ms_1677
  • MoNA: MoNA033164
  • MoNA: MoNA033165
  • MoNA: MoNA033167
  • MoNA: MoNA034862
  • MoNA: MoNA034863
  • MoNA: MoNA034865
  • MoNA: MoNA035347
  • MoNA: MoNA035348
  • MoNA: MoNA035349
  • MoNA: MoNA035350
  • MoNA: MoNA035351
  • MoNA: MoNA035353
  • MoNA: MoNA037534
  • MoNA: MoNA038284
  • MoNA: MoNA038285
  • MoNA: PR100766
  • MoNA: PR100767
  • MoNA: PR309367
  • MoNA: PR310504
  • MoNA: PS076307
  • MoNA: PS076308
  • MoNA: PS076309
  • MoNA: PT207630
  • MoNA: PT207633
  • MoNA: RIKENPlaSMA002005
  • MoNA: RIKENPlaSMA002011
  • MoNA: RIKENPlaSMA002017
  • MoNA: RIKENPlaSMA002023
  • MoNA: RIKENPlaSMA002029
  • MoNA: RIKENPlaSMA002035
  • MoNA: RIKENPlaSMA002041
  • MoNA: RIKENPlaSMA002052
  • MoNA: RIKENPlaSMA002058
  • MoNA: RIKENPlaSMA002064
  • MoNA: RIKENPlaSMA005564
  • MoNA: RIKENPlaSMA005570
  • MoNA: RIKENPlaSMA005577
  • MoNA: RIKENPlaSMA005583
  • MoNA: RIKENPlaSMA005589
  • MoNA: RIKENPlaSMA005595
  • MoNA: RIKENPlaSMA005601
  • MoNA: RIKENPlaSMA005613
  • MoNA: RIKENPlaSMA005618
  • MoNA: RIKENPlaSMA005625
  • Metlin: METLIN_305
  • Coconut NaturalProduct: CNP0335428.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R06781 C00423<=>C12621
KEGG:R06787 1.14.13.127 (2E)-3-(3-hydroxyphenyl)prop-2-enoate,NADH:oxygen oxidoreductase (2-hydroxylating)
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