Sulfur (BioCAD00000018119)

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Metabolite Card

Formula: S (31.9721)
SMILES: [S--]

Synonyms [en]

elemental sulfur; Sulfur; S(2-); sulphide; S; sulphur

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Sulfur. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000018119). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A sulfide or sulphide (UK) is an anion of sulfur in its lowest oxidation state of 2-. Sulfide is also a slightly archaic term for thioethers, a common type oforganosulfur compound that are well known for their bad odors. Sulfides are moderately strong reducing agents. They react with oxygen in the air in elevated temperatures to form higher-valence sulfur salts, such as sulfates and sulfur dioxide. (Wikipedia). Sulfur (Greek is theion) is the chemical element in the periodic table that has the symbol S and atomic number 16. It is an abundant, tasteless, odorless, multivalent non-metal. Sulfur, in its native form, is a yellow crystalline solid. In nature, it can be found as the pure element or as sulfide and sulfate minerals. It is an essential element for life, and is widely used in biochemical processes. Sulfur is an important part of many enzymes and also in antioxidant molecules like glutathione and thioredoxin. The amino acids cysteine and methionine contain sulfur, as do all polypeptides, proteins, and enzymes which contain these amino acids. This makes sulfur a necessary component of all living cells. Disulfide bonds between polypeptides are very important in protein assembly and structure. They are largely responsible for the mechanical strength and insolubility of the protein keratin, found in outer skin, hair, and feathers, and the element contributes to their pungent odor when burned. (Wikipedia). Homocysteine and taurine are also sulfur containing amino acids but are not coded for by DNA nor are they part of the primary structure of proteins. Some forms of bacteria use hydrogen sulfide (H2S) in the place of water as the electron donor in a primitive photosynthesis-like process. Sulfur is absorbed by plants via the roots from soil as the sulfate ion and reduced to sulfide before it is incorporated into cysteine and other organic sulfur compounds (sulfur assimilation). Inorganic sulfur forms a part of iron-sulfur clusters, and sulfur is the bridging ligand in the CuA site of cytochrome c oxidase. Sulfur is an important component of coenzyme A. At room temperature, sulfur is a soft bright yellow solid. Although sulfur is blamed for the smell of rotten eggs elemental sulfur has only the faintest odor (the odor associated with rotten eggs is actually due to hydrogen sulfide and organic sulfur compounds). It burns with a blue flame that emits sulfur dioxide, notable for its peculiar suffocating odor. Sulfur is insoluble in water but soluble in carbon disulfide and to a lesser extent in other organic solvents such as benzene. Through its major derivative, sulfuric acid (H2SO4), sulfur ranks as one of the more important industrial raw materials. It is of prime importance to every sector of the world's economies. The Latin name of the element is sulfur with an F. Since it is an original Latin name and not a Classical Greek loan, the fricative phoneme is indeed denoted with f rather than ph. Its commercial uses are primarily in fertilizers, but it is also widely used in gunpowder, matches, insecticides and fungicides; A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed.) The burning of coal and petroleum by industry and power plants liberates huge amounts of sulfur dioxide (SO2) which reacts with atmospheric water and oxygen to produce sulfuric acid. This sulfuric acid is a component of acid rain, which lowers the pH of soil and freshwater bodies, resulting in substantial damage to the natural environment and chemical weathering of statues and architecture.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 10544-50-0
  • CAS Registry Number: 18496-25-8
  • CAS Registry Number: 56996-94-2
  • CAS Registry Number: 7704-34-9
  • CAS Registry Number: 9035-99-8
  • PubChem: 29109
  • PubChem: 5362487
  • ChEBI: ChEBI:15138
  • ChEBI: ChEBI:17909
  • ChEBI: ChEBI:26833
  • HMDB: HMDB0000598
  • KEGG: C00087
  • BioCyc: Elemental-Sulfur
  • NCBI MeSH: Sulfides
  • NCBI MeSH: Sulfur
  • Wikipedia: Sulfide
  • Wikipedia: Sulfur
  • Coconut NaturalProduct: CNP0549616.0
  • Coconut NaturalProduct: CNP0581588.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00864 C00094 + C00087<=>C00320
KEGG:R03533 donor:sulfur oxidoreductase
KEGG:R04094 3.2.1.147 thioglucoside glucohydrolase
KEGG:R05259 1.14.14.1 parathion,NADPH---hemoprotein reductase:oxygen oxidoreductase (paraoxon-forming)
KEGG:R07365 1.13.11.55 sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming)
KEGG:R09499 1.8.2.3 hydrogen-sulfide:flavocytochrome c oxidoreductase
KEGG:R10419 1.8.1.18 hydrogen sulfide:NAD+ oxidoreductase (CoA-dependent)
KEGG:R10438 1.8.1.18 hydrogen sulfide:NADP+ oxidoreductase (CoA-dependent)
KEGG:R12631 1.8.2.7 thiocyanate:cytochrome c oxidoreductase (cyanate and sulfur-forming)
KEGG:R13121 4.8.1.5 thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming)
KEGG:R13400 3.12.1.- C02084 + C00001<=>C00320 + C00087 + C00059 + C00080
Rhea:RHEA:13542 tetrathionate + H2O => sulfur + thiosulfate + sulfate + H+
Rhea:RHEA:13543 sulfur + thiosulfate + sulfate + H+ => tetrathionate + H2O
Rhea:RHEA:13544 tetrathionate + H2O <=> sulfur + thiosulfate + sulfate + H+
Rhea:RHEA:13958 1.13.11.55 4 sulfur + O2 + 4 H2O => 2 hydrogen sulfide + 2 sulfite + 6 H+
Rhea:RHEA:13959 1.13.11.55 2 hydrogen sulfide + 2 sulfite + 6 H+ => 4 sulfur + O2 + 4 H2O
Rhea:RHEA:13960 1.13.11.55 4 sulfur + O2 + 4 H2O <=> 2 hydrogen sulfide + 2 sulfite + 6 H+
Rhea:RHEA:30224 1.8.2.3 hydrogen sulfide + 2 Fe(III)-[cytochrome c] => sulfur + 2 Fe(II)-[cytochrome c] + H+
Rhea:RHEA:30225 1.8.2.3 sulfur + 2 Fe(II)-[cytochrome c] + H+ => hydrogen sulfide + 2 Fe(III)-[cytochrome c]
Rhea:RHEA:30226 1.8.2.3 hydrogen sulfide + 2 Fe(III)-[cytochrome c] <=> sulfur + 2 Fe(II)-[cytochrome c] + H+
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Organism Source

Taxonomy Source

  1. Capparis spinosa [ncbi taxid: 65558]

Pathway Synthetic

pathway id name
BioCyc:META_PWY0-1275 lipoate biosynthesis and incorporation II
BioCyc:ECO_PWY0-1275 lipoate biosynthesis and incorporation II
BioCyc:META_PWY-721 3-methylquinoline degradation
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-OAU-2744343 Amino acid metabolism
Plant Reactome:R-MES-2744345 Metabolism and regulation
Plant Reactome:R-MES-2744343 Amino acid metabolism
Plant Reactome:R-MES-5655124 Amino acid catabolism
Plant Reactome:R-TDI-2744345 Metabolism and regulation
Plant Reactome:R-TDI-2744343 Amino acid metabolism
Plant Reactome:R-DRO-2744345 Metabolism and regulation
Plant Reactome:R-DRO-1119612 Cysteine degradation
Plant Reactome:R-PTI-2744345 Metabolism and regulation
Plant Reactome:R-PTI-2744343 Amino acid metabolism
Plant Reactome:R-PTI-5655124 Amino acid catabolism
Plant Reactome:R-GMA-2744345 Metabolism and regulation
Plant Reactome:R-GMA-2744343 Amino acid metabolism
Plant Reactome:R-PDA-2744345 Metabolism and regulation
Plant Reactome:R-PDA-2744343 Amino acid metabolism
Plant Reactome:R-PDA-1119612 Cysteine degradation
View All Pathways