Pantetheine (BioCAD00000015853)

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Metabolite Card

Formula: C11H22N2O4S (278.13)
SMILES: CC(C)(CO)C(O)C(=O)NCCC(=O)NCCS

Synonyms [en]

pantetheine; (R)-Pantetheine; D-Pantetheine; pantotheine; Lactobacillus bulgaricus factor; N-(PANTOTHENYL)-.BETA.-AMINOETHANETHIOL

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Pantetheine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000015853). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Pantetheine is the mercaptoethyl conjugated amide analogue of pantothenic acid (Vitamin B5). The dimer of this compound, pantethine is more commonly known, and is considered to be a more potent form of vitamin B5 than pantothenic acid. Pantetheine is an intermediate in the production of Coenzyme A by the body. An intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 496-65-1
  • CAS Registry Number: 50460-41-8
  • PubChem: 439322
  • PubChem: 479
  • ChEBI: ChEBI:16753
  • HMDB: HMDB0003426
  • KEGG: C00831
  • BioCyc: CPD-511
  • NCBI MeSH: Pantetheine
  • Wikipedia: Pantetheine
  • RefMet: RM0136799
  • Coconut NaturalProduct: CNP0061445.1
  • Coconut NaturalProduct: CNP0061445.2
  • Coconut NaturalProduct: CNP0300836.0
  • Coconut NaturalProduct: CNP0332663.1
  • Coconut NaturalProduct: CNP0528265.1
  • Coconut NaturalProduct: CNP0528265.2
  • Coconut NaturalProduct: CNP0552863.1
  • Coconut NaturalProduct: CNP0552863.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02971 2.7.1.33 ATP:pantothenate 4'-phosphotransferase
KEGG:R02972 4.1.1.30 N-((R)-pantothenoyl)-L-cysteine carboxy-lyase
KEGG:R02973 3.5.1.92 (R)-pantetheine amidohydrolase
KEGG:R10748 3.1.3.110 pantetheine-4'-phosphate phosphohydrolase
KEGG:R10749 C20821 + C00831<=>C20813
KEGG:R13537 4.4.1.44 (2R,3R,5S)-2-(S-pantetheinyl)-carbapenam-3-carboxylate lyase
BioCyc:PANTETHEINE-KINASE-RXN 2.7.1.34 CPD-511 + ATP --> PANTETHEINE-P + ADP + PROTON
Rhea:RHEA:13446 3.5.1.92 (R)-pantetheine + H2O => cysteamine + (R)-pantothenate
Rhea:RHEA:13447 3.5.1.92 cysteamine + (R)-pantothenate => (R)-pantetheine + H2O
Rhea:RHEA:13448 3.5.1.92 (R)-pantetheine + H2O <=> cysteamine + (R)-pantothenate
Rhea:RHEA:15078 4.1.1.30 N-[(R)-pantothenoyl]-L-cysteine + H+ => (R)-pantetheine + CO2
Rhea:RHEA:15079 4.1.1.30 (R)-pantetheine + CO2 => N-[(R)-pantothenoyl]-L-cysteine + H+
Rhea:RHEA:15080 4.1.1.30 N-[(R)-pantothenoyl]-L-cysteine + H+ <=> (R)-pantetheine + CO2
Rhea:RHEA:22473 2.7.1.34 (R)-pantetheine + ATP => (R)-4'-phosphopantetheine + ADP + H+
Rhea:RHEA:22474 2.7.1.34 (R)-4'-phosphopantetheine + ADP + H+ => (R)-pantetheine + ATP
Rhea:RHEA:22475 2.7.1.34 (R)-pantetheine + ATP <=> (R)-4'-phosphopantetheine + ADP + H+
Rhea:RHEA:68329 3.1.3.110 (R)-4'-phosphopantetheine + H2O => (R)-pantetheine + phosphate
Rhea:RHEA:68330 3.1.3.110 (R)-pantetheine + phosphate => (R)-4'-phosphopantetheine + H2O
Rhea:RHEA:68331 3.1.3.110 (R)-4'-phosphopantetheine + H2O <=> (R)-pantetheine + phosphate
BioCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN 4.1.1.30 PROTON + CPD-46 --> CPD-511 + CARBON-DIOXIDE
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]
  2. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
WikiPathways:WP3604 Biochemical pathways: part I
PathBank:SMP0120734 Malonic Aciduria
PathBank:SMP0120786 Malonyl-CoA Decarboxylase Deficiency
PathBank:SMP0120528 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0000016 Propanoate Metabolism
PathBank:SMP0087402 Propanoate Metabolism
PathBank:SMP0063656 Propanoate Metabolism
PathBank:SMP0000201 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0087341 Propanoate Metabolism
PathBank:SMP0087385 Pantothenate and CoA Biosynthesis
PathBank:SMP0063647 Pantothenate and CoA Biosynthesis
PathBank:SMP0120748 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0000027 Pantothenate and CoA Biosynthesis
PathBank:SMP0087207 Pantothenate and CoA Biosynthesis
PathBank:SMP0087248 Propanoate Metabolism
PathBank:SMP0087440 Pantothenate and CoA Biosynthesis
PathBank:SMP0087480 Propanoate Metabolism
PathBank:SMP0120514 Malonic Aciduria
PathBank:SMP0120567 Malonyl-CoA Decarboxylase Deficiency
PathBank:SMP0000198 Malonic Aciduria
View All Pathways