Neoxanthin (BioCAD00000015121)

plant natural products microbial natural products

Metabolite Card

Formula: C40H56O4 (600.4178)
SMILES: [H]C(=[C@@]=C1C(C)(C)C[C@H](O)C[C@@]1(C)O)C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(\C)/C=C/[C@@]12O[C@]1(C)C[C@@H](O)CC2(C)C

Synonyms [en]

neoxanthin; all-trans-Neoxanthin; (3S,5R,6R,3'S,5'R,6'S)-6,7-didehydro-5',6'-epoxy-5,6,5',6'-tetrahydro-beta,beta-carotene-3,5,3'-triol; trans-neoxanthin; (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL; PGYAYSRVSAJXTE-CLONMANBSA-N

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Neoxanthin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000015121). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Neoxanthin belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Xanthophylls arise by oxygenation of the carotene backbone. Neoxanthin is an intermediate in the synthesis of abscisic acid from violaxanthin. Neoxanthin has been detected, but not quantified in, several different foods, such as apples, paprikas, Valencia oranges, kiwis, globe artichokes, sparkleberries, hard wheat, and cinnamon. This could make neoxanthin a potential biomarker for the consumption of these foods. Neoxanthin has been shown to exhibit apoptotic and anti-proliferative functions (PMID: 15333710, 15333710).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 14660-91-4
  • CAS Registry Number: 30743-41-0
  • PubChem: 5281247
  • ChEBI: ChEBI:25501
  • ChEBI: ChEBI:32446
  • ChEBI: ChEBI:35306
  • HMDB: HMDB0003020
  • LipidMaps: LMPR01070290
  • KEGG: C08606
  • Wikipedia: Neoxanthin
  • MoNA: CA000089
  • MoNA: PM015419
  • Metlin: METLIN_3673
  • Metlin: METLIN_53814
  • Coconut NaturalProduct: CNP0160593.3
  • Coconut NaturalProduct: CNP0179769.1
  • Coconut NaturalProduct: CNP0362588.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R06948 5.3.99.9 violaxanthin-neoxanthin isomerase (epoxide-opening)
KEGG:R06949 C08606<=>C13431
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Organism Source

Taxonomy Source

  1. Acherontia atropus [ncbi taxid: ]
  2. Achillea macrophylla [ncbi taxid: 282746]
  3. Agave aurea [ncbi taxid: 467071]
  4. Ajuga spectabilis [ncbi taxid: 1586319]
  5. Alstroemeria revoluta [ncbi taxid: 198691]
  6. Ardisia quinquegona [ncbi taxid: 648860]
  7. Astragalus tragacantha [ncbi taxid: 858344]
  8. Baphia nitida [ncbi taxid: 162666]
  9. Callistemon viminalis [ncbi taxid: 73737]
  10. Cissus pallidiflorus [ncbi taxid: ]
  11. Crataegus davisii [ncbi taxid: ]
  12. Crinum erubescens [ncbi taxid: 209093]
  13. Cupressus lawsoniana [ncbi taxid: ]
  14. Emilia sonchifolia [ncbi taxid: 415160]
  15. Encephalartos altensteinii [ncbi taxid: 3300]
  16. Eria foetida [ncbi taxid: ]
  17. Eupatorium havanense [ncbi taxid: ]
  18. Euphorbia kamerunica [ncbi taxid: ]
  19. Euphorbia marginata [ncbi taxid: 28955]
  20. Excoecaria oppositifolia [ncbi taxid: 3389821]
  21. Gardenia collinsae [ncbi taxid: 1233748]
  22. Grindelia acutifolia [ncbi taxid: ]
  23. Guanomyces polythrix [ncbi taxid: 110160]
  24. Gymnosporia senegalensis [ncbi taxid: 256095]
  25. Ircinia oros [ncbi taxid: 1141585]
  26. Junceella fragilis [ncbi taxid: 98366]
  27. Jungermannia hyalina [ncbi taxid: ]
  28. Kobresia nepalensis [ncbi taxid: ]
  29. Ligularia muliensis [ncbi taxid: 2126609]
  30. Litsea aciculata [ncbi taxid: ]
  31. Litsea pulchella [ncbi taxid: ]
  32. Marrubium alysson [ncbi taxid: 694370]
  33. Melampodium heterophyllum [ncbi taxid: ]
  34. Myrmica sabuleti [ncbi taxid: 229917]
  35. Mytilus edulis [ncbi taxid: 6550]
  36. Nuphar lutea [ncbi taxid: 77113]
  37. Pausinystalia mayumbensis [ncbi taxid: ]
  38. Penicillium olsonii [ncbi taxid: 99116]
  39. Pentzia incana [ncbi taxid: 379275]
  40. Perilla frutescens var. arguta [ncbi taxid: 381201]
  41. Prangos pabularia [ncbi taxid: 52497]
  42. Pronephrium triphyllum [ncbi taxid: ]
  43. Selliguea feei [ncbi taxid: 194882]
  44. Shuteria involucrata var. vestita [ncbi taxid: 132463]
  45. Simaba multiflora [ncbi taxid: ]
  46. Sinocalamus affinis [ncbi taxid: ]
  47. Stevia chamaedrys [ncbi taxid: ]
  48. Teucrium oxylepis [ncbi taxid: 1209881]
  49. Trifolium subterraneum [ncbi taxid: 3900]
  50. Trillium camschatcense [ncbi taxid: 49675]
  51. Ursinia abrotanifolia [ncbi taxid: 3122733]
  52. Xenorhabdus bovienii [ncbi taxid: 40576]
  53. Acalypha wilkesiana [ncbi taxid: 217498]
  54. Aceriphyllum rossii [ncbi taxid: ]
  55. Agnorhiza bolanderi [ncbi taxid: 230216]
  56. Alligator mississippiensis [ncbi taxid: 8496]
  57. Anaxagorea clavata [ncbi taxid: ]
  58. Ankistrodesmus spp. [ncbi taxid: ]
  59. Arabidopsis thaliana [ncbi taxid: 3702]
  60. Araujia sericifera [ncbi taxid: 63463]
  61. Aria pallescens [ncbi taxid: ]
  62. Arnica nevadensis [ncbi taxid: 436208]
  63. Arousa sp. [ncbi taxid: ]
  64. Artemisia monogyna [ncbi taxid: 1903222]
  65. Ascophyllum nodosum [ncbi taxid: 52969]
  66. Baphicacanthus cusia [ncbi taxid: ]
  67. Bassia butyracea [ncbi taxid: ]
  68. Bathycoccus prasinos [ncbi taxid: 41875]
  69. Beyeria brevifolia [ncbi taxid: 2752376]
  70. Boronia megastigma [ncbi taxid: 709985]
  71. Botryococcus braunii [ncbi taxid: 38881]
  72. Botryococcus braunii Kawaguchi-1 [ncbi taxid: ]
  73. Brickellia cylindracea [ncbi taxid: 1550813]
  74. Bursaria spinosa [ncbi taxid: 105281]
  75. Cacospongia scalaris [ncbi taxid: ]
  76. Calendula officinalis [ncbi taxid: 41496]
  77. Calocephalus citreus [ncbi taxid: ]
  78. Caltha palustris [ncbi taxid: 3449]
  79. Capsicum annuum [ncbi taxid: 4072]
  80. Cetraria australiensis [ncbi taxid: 425280]
  81. Chara aspera [ncbi taxid: 69330]
  82. Chara contraria [ncbi taxid: 69334]
  83. Chara foetida [ncbi taxid: ]
  84. Chara globularis [ncbi taxid: 69338]
  85. Chara gymnophylla [ncbi taxid: 1658605]
  86. Chara hispida [ncbi taxid: 37303]
  87. Chara intermedia [ncbi taxid: ]
  88. Chara polyacantha [ncbi taxid: ]
  89. Chara rudis [ncbi taxid: 1304951]
  90. Chara tomentosa [ncbi taxid: 69346]
  91. Chara vulgaris [ncbi taxid: 55564]
  92. Chlamydomonas parkeae [ncbi taxid: 156093]
  93. Chlamydomonas reinhardtii [ncbi taxid: 3055]
  94. Chloranthus tianmushanensis [ncbi taxid: ]
  95. Chlorella pyrenoidosa [ncbi taxid: ]
  96. Chromolaena odorata [ncbi taxid: 103745]
  97. Chromolaena pulchella [ncbi taxid: ]
  98. Citrullus lanatus [ncbi taxid: 3654]
  99. Citrullus vulgaris [ncbi taxid: ]
  100. Citrus reticulata [ncbi taxid: 85571]
  101. Cladonia evansii [ncbi taxid: 197026]
  102. Cladonia sp. [ncbi taxid: 2040733]
  103. Clonostachys rosea [ncbi taxid: 29856]
  104. Coccus fagi [ncbi taxid: ]
  105. Coffea arabica [ncbi taxid: 13443]
  106. Coffea canephora [ncbi taxid: 49390]
  107. Crotalaria medicaginea [ncbi taxid: 466929]
  108. Croton megistocarpus [ncbi taxid: 425923]
  109. Cytisus scoparius [ncbi taxid: 3835]
  110. Daemonorops draco [ncbi taxid: ]
  111. Dendrosenecio kilimanjari [ncbi taxid: 109559]
  112. Dipterocarpus alatus [ncbi taxid: 340438]
  113. Drosera peltata [ncbi taxid: 4369]
  114. Echinops amplexicaulis [ncbi taxid: 910522]
  115. Epaltes gariepina [ncbi taxid: 1548596]
  116. Eria alba [ncbi taxid: ]
  117. Eria floribunda [ncbi taxid: ]
  118. Euglena gracilis [ncbi taxid: 3039]
  119. Euglena gracilis var. bacillarus [ncbi taxid: ]
  120. Euglena rubida mainx [ncbi taxid: ]
  121. Euglena sanguinea [ncbi taxid: 130315]
  122. Euglena viridis [ncbi taxid: 3040]
  123. Eutreptiella gymnastica [ncbi taxid: 73025]
  124. Excoecaria acerifolia [ncbi taxid: 2054263]
  125. Ficus formosana [ncbi taxid: 1127366]
  126. Forsythia spp. [ncbi taxid: ]
  127. Fritillaria stenanthera [ncbi taxid: 83801]
  128. Fucus serratus [ncbi taxid: 87148]
  129. Fucus vesiculosus [ncbi taxid: 49266]
  130. Fusarium avenaceum [ncbi taxid: 40199]
  131. Fusarium gibbosum [ncbi taxid: 2126134]
  132. Fusarium sacchari [ncbi taxid: 42676]
  133. Gardenia fosbergii [ncbi taxid: ]
  134. Garrya laurifolia [ncbi taxid: 1197921]
  135. Genista pichisermolliana [ncbi taxid: ]
  136. Geranium sibiricum [ncbi taxid: 345237]
  137. Geum spp. [ncbi taxid: ]
  138. Gonyostomum semen [ncbi taxid: 375454]
  139. Goupia glabra [ncbi taxid: 39314]
  140. Helipterum gnaphaloides [ncbi taxid: ]
  141. Hippophae rhamnoides [ncbi taxid: 193516]
  142. Ilex affinis [ncbi taxid: 185489]
  143. Isodon kameba [ncbi taxid: ]
  144. Kaempferia pulchra [ncbi taxid: 199647]
  145. Kopsia teoi [ncbi taxid: ]
  146. Lactarius scrobiculatus [ncbi taxid: 93011]
  147. Lagerstroemia indica [ncbi taxid: 141186]
  148. Laggera alata [ncbi taxid: 441197]
  149. Laminaria digitata [ncbi taxid: 80365]
  150. Laminaria saccharina [ncbi taxid: ]
  151. Lithothamnion corallioides [ncbi taxid: 1277934]
  152. Lycium barbarum [ncbi taxid: 112863]
  153. Lycium chinense [ncbi taxid: 112883]
  154. Malus domestica [ncbi taxid: 3750]
  155. Malus spp. [ncbi taxid: ]
  156. Mangifera indica [ncbi taxid: 29780]
  157. Mantoniella squamata [ncbi taxid: 13608]
  158. Medinilla magnifica [ncbi taxid: 1799599]
  159. Mesua ferrea [ncbi taxid: 210380]
  160. Micromonas pusilla [ncbi taxid: 38833]
  161. Monnieria trifolia [ncbi taxid: ]
  162. Monopteryx uaucu [ncbi taxid: 1602310]
  163. Moringa oleifera [ncbi taxid: 3735]
  164. Nephroselmis olivace [ncbi taxid: ]
  165. Nephroselmis pyriformis [ncbi taxid: 156128]
  166. Nephroselmis rotunda [ncbi taxid: 344402]
  167. Nitella opaca [ncbi taxid: 97465]
  168. Ochromonas sp. [ncbi taxid: 1955567]
  169. Odixia angusta [ncbi taxid: 125740]
  170. Oedogonium cardiacum [ncbi taxid: 55995]
  171. Olisthodiscus luteus [ncbi taxid: 83000]
  172. Onobrychis bobrovii [ncbi taxid: 872932]
  173. Oryza sativa [ncbi taxid: 4530]
  174. Papaver persicum [ncbi taxid: 3116565]
  175. Passiflora edulis [ncbi taxid: 78168]
  176. Pelvetia canaliculata [ncbi taxid: 74467]
  177. Persea americana [ncbi taxid: 3435]
  178. Persea kusanoi [ncbi taxid: ]
  179. Petteria ramentacea [ncbi taxid: 49832]
  180. Pheidole pallidula [ncbi taxid: 190770]
  181. Pleurastrum paucicellulare [ncbi taxid: ]
  182. Podospora curvicolla [ncbi taxid: ]
  183. Polyalthia barnesii [ncbi taxid: ]
  184. Polyporus pargamenus [ncbi taxid: ]
  185. Potamogeton perfoliatus [ncbi taxid: 55320]
  186. Poterioochromonas malhamensis [ncbi taxid: 88167]
  187. Pouteria sapota [ncbi taxid: 233744]
  188. Prasinococcus capsulatus [ncbi taxid: 156131]
  189. Prosopis glandulosa [ncbi taxid: ]
  190. Protosiphon botryoides [ncbi taxid: 44656]
  191. Protousnea sp. [ncbi taxid: ]
  192. Prunus domestica [ncbi taxid: 3758]
  193. Prunus laurocerasus [ncbi taxid: 32242]
  194. Prunus persica [ncbi taxid: 3760]
  195. Pseudopterogorgia kallos [ncbi taxid: ]
  196. Pseudoscourfieldia marina [ncbi taxid: 41886]
  197. Psychotria st [ncbi taxid: ]
  198. Pteris prolifera [ncbi taxid: ]
  199. Pterocarpus grandiflorus [ncbi taxid: ]
  200. Pycnococcus provasolii [ncbi taxid: 41880]
  201. Pyramimonas amylifera [ncbi taxid: ]
  202. Pyrosoma giganteum [ncbi taxid: ]
  203. Quercus aegilops [ncbi taxid: ]
  204. Rhizobium phaseoli [ncbi taxid: 396]
  205. Rubus lambertianus [ncbi taxid: 75113]
  206. Salvia officinalis [ncbi taxid: 38868]
  207. Securidaca inappendiculata [ncbi taxid: 3091905]
  208. Senecio cathcartensis [ncbi taxid: 1886426]
  209. Senecio isatideus [ncbi taxid: ]
  210. Senecio squalidus [ncbi taxid: 121554]
  211. Sequoia sempervirens [ncbi taxid: 28980]
  212. Seriphidium cinum [ncbi taxid: ]
  213. Sesbania punicea [ncbi taxid: 543741]
  214. Sidastrum burrerense [ncbi taxid: ]
  215. Simira eliezeriana [ncbi taxid: ]
  216. Solorina crocea [ncbi taxid: 48864]
  217. Spinacia oleracea L. [ncbi taxid: ]
  218. Stenostomum lucidum [ncbi taxid: 43446]
  219. Stevia paniculata [ncbi taxid: ]
  220. Streptomyces althioticus [ncbi taxid: 83380]
  221. Striga lutea [ncbi taxid: ]
  222. Tagetes erecta L. [ncbi taxid: ]
  223. Taxodium mucronatum [ncbi taxid: 99812]
  224. Tetraselmis sp. [ncbi taxid: 2812566]
  225. Tetraselmis wettsteinii [ncbi taxid: 1689752]
  226. Trifolium strepens [ncbi taxid: ]
  227. Trigonella foenum-graecum [ncbi taxid: 78534]
  228. Vitex madiensis [ncbi taxid: 1899206]
  229. Yucca recurvifolia [ncbi taxid: 1182952]
  230. Zostera marina [ncbi taxid: 29655]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-695 abscisic acid biosynthesis
BioCyc:META_PWY-7950 diadinoxanthin and fucoxanthin biosynthesis
BioCyc:META_PWY-6809 neoxanthin biosynthesis
BioCyc:META_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
Plant Reactome:R-OSA-9608520 Abscisic acid homeostasis
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2744341 Hormone signaling, transport, and metabolism
Plant Reactome:R-OSA-3899368 ABA biosynthesis and mediated signaling
Plant Reactome:R-OSA-2744344 Secondary metabolism
Plant Reactome:R-OSA-1119449 Carotenoid biosynthesis
Plant Reactome:R-OSA-1119374 ABA synthesis
PlantCyc:SFALLAX_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:VALLEYOAK_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:PHALLII_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:AHALLERI_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:CACUMINATA_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:DROTUNDATA_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:EUROPEANPEAR_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:BRACHYPODIUM_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
PlantCyc:POPLAR_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
View All Pathways