1,1-Dichloroethylene epoxide (BioCAD00000001507)

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Metabolite Card

Formula: C2H2Cl2O (111.9483)
SMILES: ClC1(Cl)CO1

Synonyms [en]

2,2-Dichlorooxirane; 1,1-Dichloroethylene epoxide; dichloroethane ether; UNII-7L2MY8DN4Q; 7L2MY8DN4Q; AKOS006273462

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

1,1-Dichloroethylene epoxide. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000001507). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

1,1-Dichloroethylene epoxide, also known as DCE epoxide is a compound belonging to the family of compounds known as orthocarboxylic acid derivatives. These are organic compounds containing the orhtocarboxylic acid functional group, with the RC(X)(X)X (R=H, alkyl,aryl; X=OH,alkoxy,aryloxy, (substituted amino), etc. (PMID: 16098521). Epoxides are compounds containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms). DCE epoxide is a urinary metabolite of 1,1-Dichloroethene (DCE), or vinylidine chloride (PMID: 15319346, 11270662). DCE is mainly used as a comonomer in the production and polymerization of plastics such as polyvinyl chloride, acrylonitrile, and acrylates. As a result, DCE is widely distributed in the environment and in plastics. DCE was the precursor to the original form of saran-wrap or cling-wrap (clear plastic wrap used to preserve foods), but this has been phased out due to concerns over the carcinogenicity of DCE.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 68226-83-5
  • PubChem: 119521
  • ChEBI: ChEBI:34032
  • HMDB: HMDB0060333
  • KEGG: C14857
  • NCBI MeSH: 1,1-dichloroethylene epoxide
  • Metlin: METLIN_70362
  • Coconut NaturalProduct: CNP0513034.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R07089 1.14.14.- 1,1-dichloroethylene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
KEGG:R07092 2.5.1.18 1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]
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Organism Source

Taxonomy Source

  1. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
WikiPathways:WP3666 Metabolism of dichloroethylene by CYP450
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