Isatin (BioCAD00000012505)
Metabolite Card
Formula: C8H5NO2 (147.032)
SMILES: O=C1NC2=CC=CC=C2C1=O
Synonyms [en]
Isatin; 1H-Indole-2,3-dione; INDOLE-2,3-DIONE; AI3-03111; 3-hydroxy-2-indolone; 2,3-Dioxoindoline
Last reviewed on 2024-06-28.
Cite this Page
Isatin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000012505). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
1H-Indole-2,3-dione belongs to the class of organic compounds known as indolines. These are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole.
DBLinks
- CAS Registry Number: 91-56-5
- PubChem CID: 7054
- ChEBI: 27539
- HMDB: HMDB0061933
- LipidMaps:
- KEGG: C11129
- BioCyc: ISATIN
- NCBI MeSH: Isatin
- Wikipedia: Isatin
Other DBLinks
- CAS Registry Number: 84788-92-1
- CAS Registry Number: 91-56-5
- PubChem: 13311
- PubChem: 7054
- ChEBI: ChEBI:27539
- HMDB: HMDB0061933
- KEGG: C11129
- BioCyc: ISATIN
- NCBI MeSH: Isatin
- Wikipedia: Isatin
- DrugBank: DB02095
- RefMet: RM0204181
- MoNA: FIO00510
- MoNA: FIO00511
- MoNA: FIO00512
- MoNA: FIO00513
- MoNA: FIO00514
- MoNA: KO001196
- MoNA: KO001197
- MoNA: KO001198
- MoNA: KO001199
- MoNA: KO001200
- MoNA: KO003197
- MoNA: KO003198
- MoNA: KO003199
- MoNA: KO003200
- MoNA: KO003201
- Metlin: METLIN_68870
- Coconut NaturalProduct: CNP0320767.0
Class / Ontology
- WishartLab ClassyFire: [Indolines] Indolines
- RefMet: [Simple oxindole alkaloids] Simple oxindole alkaloids
- ChEBI: [CHEBI:27539] isatin
- Coconut NaturalProduct: [Simple oxindole alkaloids] Simple oxindole alkaloids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R11181 | 3.5.2.20 | isatin amidohydrolase |
| Rhea:RHEA:43233 | 3.5.2.20 | isatin + H2O => isatinate + H+ |
| Rhea:RHEA:43234 | 3.5.2.20 | isatinate + H+ => isatin + H2O |
| Rhea:RHEA:43235 | 3.5.2.20 | isatin + H2O <=> isatinate + H+ |
| Rhea:RHEA:68609 | isatin + NADPH + H+ => 3-hydroxyindolin-2-one + NADP+ | |
| Rhea:RHEA:68610 | 3-hydroxyindolin-2-one + NADP+ => isatin + NADPH + H+ | |
| Rhea:RHEA:68611 | isatin + NADPH + H+ <=> 3-hydroxyindolin-2-one + NADP+ | |
| BioCyc:RXN-3944 | 3.5.2.20 | ISATIN + WATER --> PROTON + ALPHA-AMINOPHENYL-GLYOXYLATE |
| BioCyc:RXN-3943 | 1.1.-.- | CPD-6362 + Acceptor --> ISATIN + Donor-H2 |
Taxonomy Source
- Alteromonas sp. [ncbi taxid: 232]
- Baphicacanthus cusia [ncbi taxid: ]
- Calanthe discolor Lindl [ncbi taxid: ]
- Calanthe liukiuensis Schltr [ncbi taxid: ]
- Capparis spinosa [ncbi taxid: 65558]
- Cephalanceropsis gracilis [ncbi taxid: ]
- Homo sapiens [ncbi taxid: 9606]
- Isatis indigotica [ncbi taxid: 3242077]
- Isatis tinctoria [ncbi taxid: 161756]
- Persicaria tinctoria [ncbi taxid: 96455]
- Senecio longifolius [ncbi taxid: 2962179]
- Senecio paucicazyculatus [ncbi taxid: ]
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:META_PWY-2421 | indole-3-acetate degradation |