Hydroxypyruvate (BioCAD00000012265)

blood feces urine

Metabolite Card

Formula: C3H4O4 (104.011)
SMILES: OCC(=O)C(O)=O

Synonyms [en]

Hydroxypyruvic acid; 3-HYDROXYPYRUVIC ACID; Hydroxypyruvate; 3-Hydroxy-2-oxopropanoic acid; beta-Hydroxypyruvate; OH-pyruvate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Hydroxypyruvate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000012265). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Hydroxypyruvic acid is an intermediate in the metabolism of Glycine, serine and threonine. It is a substrate for Serine--pyruvate aminotransferase and Glyoxylate reductase/hydroxypyruvate reductase.

Mitochondria Peroxisome
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1113-60-6
  • CAS Registry Number: 131000-16-3
  • PubChem: 3468
  • PubChem: 964
  • ChEBI: ChEBI:17180
  • ChEBI: ChEBI:30841
  • HMDB: HMDB0001352
  • KEGG: C00168
  • NCBI MeSH: hydroxypyruvic acid
  • Wikipedia: Hydroxypyruvic_acid
  • DrugBank: DB02951
  • RefMet: RM0139953
  • MoNA: EMBL-MCF_spec54883
  • MoNA: FiehnLib000635
  • MoNA: FiehnLib001066
  • MoNA: GLS00061
  • MoNA: GLS00062
  • MoNA: HMDB0001352_c_ms_987
  • MoNA: HMDB0001352_c_ms_993
  • MoNA: MoNA024048
  • MoNA: OUF00055
  • MoNA: OUF00056
  • Metlin: METLIN_482
  • Coconut NaturalProduct: CNP0343498.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00581 1.4.1.7 L-serine:NAD+ oxidoreductase (deaminating)
KEGG:R00585 2.6.1.51 L-serine:pyruvate aminotransferase
KEGG:R00588 2.6.1.45 L-serine:glyoxylate aminotransferase
KEGG:R01388 1.1.1.26 D-glycerate:NAD+ 2-oxidoreductase
KEGG:R01390 C00168 + C00011<=>C00975
KEGG:R01392 1.1.1.79 D-glycerate:NADP+ 2-oxidoreductase
KEGG:R01393 4.1.1.40 hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)
KEGG:R01394 5.3.1.22 hydroxypyruvate aldose-ketose-isomerase
Rhea:RHEA:11953 5.3.1.22 3-hydroxypyruvate => 2-hydroxy-3-oxopropanoate
Rhea:RHEA:11954 5.3.1.22 2-hydroxy-3-oxopropanoate => 3-hydroxypyruvate
Rhea:RHEA:11955 5.3.1.22 3-hydroxypyruvate <=> 2-hydroxy-3-oxopropanoate
Rhea:RHEA:17906 1.1.1.29 (R)-glycerate + NAD+ => 3-hydroxypyruvate + NADH + H+
Rhea:RHEA:17907 1.1.1.29 3-hydroxypyruvate + NADH + H+ => (R)-glycerate + NAD+
Rhea:RHEA:17908 1.1.1.29 (R)-glycerate + NAD+ <=> 3-hydroxypyruvate + NADH + H+
Rhea:RHEA:18658 1.1.1.81 (R)-glycerate + NADP+ => 3-hydroxypyruvate + NADPH + H+
Rhea:RHEA:18659 1.1.1.81 3-hydroxypyruvate + NADPH + H+ => (R)-glycerate + NADP+
Rhea:RHEA:18660 1.1.1.81 (R)-glycerate + NADP+ <=> 3-hydroxypyruvate + NADPH + H+
Rhea:RHEA:19126 2.6.1.45 glyoxylate + L-serine => 3-hydroxypyruvate + glycine
Rhea:RHEA:19127 2.6.1.45 3-hydroxypyruvate + glycine => glyoxylate + L-serine
Rhea:RHEA:19128 2.6.1.45 glyoxylate + L-serine <=> 3-hydroxypyruvate + glycine
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