Hydrochlorothiazide (BioCAD00000012207)
blood feces urine adipose tissue kidney platelet plant natural products
Metabolite Card
Formula: C7H8ClN3O4S2 (296.9645)
SMILES: NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
Synonyms [en]
hydrochlorothiazide; Hidril; Bremil; Dihydrochlorothiazide; Hydrosaluric; Cidrex
Last reviewed on 2024-06-28.
Cite this Page
Hydrochlorothiazide. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000012207). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Hydrochlorothiazide is a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. -- Pubchem. Hydrochlorothiazide (Apo-Hydro, Aquazide H, Microzide, Oretic), sometimes abbreviated HCT, HCTZ, or HZT is a popular diuretic drug that acts by inhibiting the kidney's ability to retain water. This reduces the volume of the blood, decreasing peripheral vascular resistance. Chlorothiazide, a carbonic anhydrase inhibitor. --Wikipedia.
DBLinks
- CAS Registry Number: 58-93-5
- PubChem CID: 3639
- ChEBI: 5778
- HMDB: HMDB0001928
- LipidMaps:
- KEGG: C07041
- BioCyc:
- NCBI MeSH: Hydrochlorothiazide
- Wikipedia: Hydrochlorothiazide
Other DBLinks
- CAS Registry Number: 125727-50-6
- CAS Registry Number: 58-93-5
- CAS Registry Number: 8049-49-8
- PubChem: 3639
- ChEBI: ChEBI:5778
- HMDB: HMDB0001928
- HMDB: HMDB01928
- KEGG: C07041
- KEGG: D00340
- NCBI MeSH: Hydrochlorothiazide
- Wikipedia: Hydrochlorothiazide
- DrugBank: DB00999
- RefMet: RM0136135
- MoNA: EA261001
- MoNA: EA261002
- MoNA: EA261003
- MoNA: EA261004
- MoNA: EA261005
- MoNA: EA261006
- MoNA: EA261007
- MoNA: EA261008
- MoNA: EA261009
- MoNA: EA261010
- MoNA: EA261011
- MoNA: EA261012
- MoNA: EA261013
- MoNA: EA261014
- MoNA: EA261051
- MoNA: EA261052
- MoNA: EA261053
- MoNA: EA261054
- MoNA: EA261055
- MoNA: EA261056
- MoNA: EA261057
- MoNA: EA261058
- MoNA: EA261059
- MoNA: EA261060
- MoNA: EA261061
- MoNA: EA261062
- MoNA: EA261063
- MoNA: EA261064
- MoNA: HMDB0001928_ms_ms_1863
- MoNA: HMDB0001928_ms_ms_1864
- MoNA: HMDB0001928_ms_ms_1865
- MoNA: LU051451
- MoNA: LU051452
- MoNA: LU051453
- MoNA: LU051454
- MoNA: LU051455
- MoNA: LU051456
- MoNA: TUE00375
- MoNA: TUE00376
- MoNA: TUE00377
- MoNA: VF-NPL-LTQ000483
- MoNA: VF-NPL-LTQ000484
- MoNA: VF-NPL-QTOF007999
- MoNA: VF-NPL-QTOF008000
- MoNA: VF-NPL-QTOF008001
- MoNA: WA000335
- MoNA: WA000336
- MoNA: WA000337
- MoNA: WA000338
- MoNA: WA000339
- Metlin: METLIN_3169
- Coconut NaturalProduct: CNP0212821.0
Class / Ontology
- WishartLab ClassyFire: [Benzothiadiazines] Benzothiadiazines
- RefMet: [Benzothiadiazines] Benzothiadiazines
- ChEBI: [CHEBI:5778] hydrochlorothiazide
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0000100 | Hydrochlorothiazide Action Pathway |