Hydrochlorothiazide (BioCAD00000012207)

blood feces urine adipose tissue kidney platelet plant natural products

Metabolite Card

Formula: C7H8ClN3O4S2 (296.9645)
SMILES: NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1

Synonyms [en]

hydrochlorothiazide; Hidril; Bremil; Dihydrochlorothiazide; Hydrosaluric; Cidrex

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Hydrochlorothiazide. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000012207). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Hydrochlorothiazide is a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. -- Pubchem. Hydrochlorothiazide (Apo-Hydro, Aquazide H, Microzide, Oretic), sometimes abbreviated HCT, HCTZ, or HZT is a popular diuretic drug that acts by inhibiting the kidney's ability to retain water. This reduces the volume of the blood, decreasing peripheral vascular resistance. Chlorothiazide, a carbonic anhydrase inhibitor. --Wikipedia.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 125727-50-6
  • CAS Registry Number: 58-93-5
  • CAS Registry Number: 8049-49-8
  • PubChem: 3639
  • ChEBI: ChEBI:5778
  • HMDB: HMDB0001928
  • HMDB: HMDB01928
  • KEGG: C07041
  • KEGG: D00340
  • NCBI MeSH: Hydrochlorothiazide
  • Wikipedia: Hydrochlorothiazide
  • DrugBank: DB00999
  • RefMet: RM0136135
  • MoNA: EA261001
  • MoNA: EA261002
  • MoNA: EA261003
  • MoNA: EA261004
  • MoNA: EA261005
  • MoNA: EA261006
  • MoNA: EA261007
  • MoNA: EA261008
  • MoNA: EA261009
  • MoNA: EA261010
  • MoNA: EA261011
  • MoNA: EA261012
  • MoNA: EA261013
  • MoNA: EA261014
  • MoNA: EA261051
  • MoNA: EA261052
  • MoNA: EA261053
  • MoNA: EA261054
  • MoNA: EA261055
  • MoNA: EA261056
  • MoNA: EA261057
  • MoNA: EA261058
  • MoNA: EA261059
  • MoNA: EA261060
  • MoNA: EA261061
  • MoNA: EA261062
  • MoNA: EA261063
  • MoNA: EA261064
  • MoNA: HMDB0001928_ms_ms_1863
  • MoNA: HMDB0001928_ms_ms_1864
  • MoNA: HMDB0001928_ms_ms_1865
  • MoNA: LU051451
  • MoNA: LU051452
  • MoNA: LU051453
  • MoNA: LU051454
  • MoNA: LU051455
  • MoNA: LU051456
  • MoNA: TUE00375
  • MoNA: TUE00376
  • MoNA: TUE00377
  • MoNA: VF-NPL-LTQ000483
  • MoNA: VF-NPL-LTQ000484
  • MoNA: VF-NPL-QTOF007999
  • MoNA: VF-NPL-QTOF008000
  • MoNA: VF-NPL-QTOF008001
  • MoNA: WA000335
  • MoNA: WA000336
  • MoNA: WA000337
  • MoNA: WA000338
  • MoNA: WA000339
  • Metlin: METLIN_3169
  • Coconut NaturalProduct: CNP0212821.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]
  2. Rhus chinensis [ncbi taxid: 289753]

Pathway Synthetic

pathway id name
PathBank:SMP0000100 Hydrochlorothiazide Action Pathway
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