CDP-DG(18:2(9Z,11Z)/i-12:0) (BioCAD00000110275)

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Metabolite Card

Formula: C42H73N3O15P2 (921.4517)
SMILES: [H][C@@](COC(=O)CCCCCCC\C=C/C=C\CCCCCC)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1O)N1C=CC(N)=NC1=O)OC(=O)CCCCCCCCC(C)C

Synonyms [en]

CDP-DG(18:2(9Z,11Z)/i-12:0); CDP-diacylglycerol(18:2/i-12:0); [(2R)-3-[[[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-(10-methylundecanoyloxy)propyl] (9Z,11Z)-octadeca-9,11-dienoate; {[(2R,3R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy[(2R)-2-[(10-methylundecanoyl)oxy]-3-[(9Z,11Z)-octadeca-9,11-dienoyloxy]propoxy]phosphoryl}oxy)phosphinate; CDP-DG(30:2); {[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({hydroxy[(2R)-2-[(10-methylundecanoyl)oxy]-3-[(9Z,11Z)-octadeca-9,11-dienoyloxy]propoxy]phosphoryl}oxy)phosphinic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

CDP-DG(18:2(9Z,11Z)/i-12:0). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000110275). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

CDP-DG(18:2(9Z,11Z)/i-12:0) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol (CDP-DG). CDP-diacylglycerol is an important branchpoint intermediate in eukaryotic phospholipid biosynthesis and could be a key regulatory molecule in phospholipid metabolism. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. CDP-DG(18:2(9Z,11Z)/i-12:0), in particular, consists of one chain of (9Z,11Z)-octadecadienoic acid at the C-1 position and one chain of isododecanoic acid at the C-2 position. Cytidine diphosphate diacylglycerols are rarely noticed in analyses of lipid compositions of tissues, as they are present is such small amounts (perhaps only 0.05% or so of the total phospholipids).

Entity Information

DBLinks

Other DBLinks
  • PubChem: 131822708
  • ChEBI: ChEBI:180871
  • HMDB: HMDB0116052

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PathBank:SMP0043973 Cardiolipin Biosynthesis CL(a-13:0/a-15:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0044617 Cardiolipin Biosynthesis CL(a-13:0/a-21:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0046874 Cardiolipin Biosynthesis CL(a-13:0/i-17:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0047842 Cardiolipin Biosynthesis CL(a-13:0/i-20:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0050420 Cardiolipin Biosynthesis CL(i-12:0/a-21:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0052361 Cardiolipin Biosynthesis CL(i-12:0/i-16:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0053330 Cardiolipin Biosynthesis CL(i-12:0/i-19:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0055592 Cardiolipin Biosynthesis CL(i-13:0/a-15:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0061653 Cardiolipin Biosynthesis CL(i-14:0/i-12:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0043328 Cardiolipin Biosynthesis CL(a-13:0/18:2(9Z,11Z)/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0044940 Cardiolipin Biosynthesis CL(a-13:0/a-25:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0045264 Cardiolipin Biosynthesis CL(a-13:0/i-12:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0045585 Cardiolipin Biosynthesis CL(a-13:0/i-13:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0047197 Cardiolipin Biosynthesis CL(a-13:0/i-18:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0048161 Cardiolipin Biosynthesis CL(a-13:0/i-21:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0048806 Cardiolipin Biosynthesis CL(a-13:0/i-24:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0050743 Cardiolipin Biosynthesis CL(i-12:0/a-25:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0051068 Cardiolipin Biosynthesis CL(i-12:0/i-12:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0051392 Cardiolipin Biosynthesis CL(i-12:0/i-13:0/18:2(9Z,11Z)/i-12:0)
PathBank:SMP0051716 Cardiolipin Biosynthesis CL(i-12:0/i-14:0/18:2(9Z,11Z)/i-12:0)
View All Pathways