(Z)-But-2-ene-1,2,3-tricarboxylate (BioCAD00000001050)

microbial natural products

Metabolite Card

Formula: C7H8O6 (188.0321)
SMILES: C\C(C(O)=O)=C(/CC(O)=O)C(O)=O

Synonyms [en]

cis-2-Methylaconitate; (Z)-But-2-ene-1,2,3-tricarboxylate; (Z)-but-2-ene-1,2,3-tricarboxylic acid; cis-2-Butene-1,2,3-tricarboxylic acid; (2Z)-but-2-ene-1,2,3-tricarboxylic acid; alpha-Methyl-cis-aconitate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(Z)-But-2-ene-1,2,3-tricarboxylate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000001050). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

cis-2-Methylaconitate is produced due to the dehydration of 2-methylcitrate in 2-methylcitric acid cycle. The cycle is catalyzed by a cofactor-less (PrpD) enzyme or by an aconitase-like (AcnD) enzyme. (PMID: 17567742). cis-2-Methylaconitate has been found to be a microbial metabolite (ECMDB).

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 6061-93-4
  • PubChem: 3080625
  • ChEBI: ChEBI:16717
  • HMDB: HMDB0006357
  • HMDB: HMDB06357
  • KEGG: C04225
  • NCBI MeSH: alpha-methylaconitate
  • RefMet: RM0136308
  • Metlin: METLIN_58403
  • Coconut NaturalProduct: CNP0152616.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04424 4.2.1.79 (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]
KEGG:R04425 4.2.1.99 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase
KEGG:R11264 5.3.3.- C21250<=>C04225
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Organism Source

Taxonomy Source

  1. Escherichia coli [ncbi taxid: 562]
  2. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
PathBank:SMP0000957 Propanoate Metabolism
PathBank:SMP0121322 Propanoate Metabolism
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