EC: 3.4.22.62

caspase-9 ()

enzyme lambda metabolic reaction experiment
- [caspase-9(Enzyme) wildtype]

Apaf_1_Caspase_9_cleaved_complex + Caspase_3 -> Apaf_1_Caspase_9_cleaved_complex + Caspase_3_cleaved		 (( (( (cytosol * k7) ) * C3) ) * AC9_star) buffer: *
PH: 7
Temperature: 36
- [caspase-9(Enzyme) wildtype]

Caspase_9_cleaved + Caspase_3 -> Caspase_3_cleaved + Caspase_9_cleaved		 (( (( (cytosol * k6) ) * C3) ) * C9_star) buffer: *
PH: 7
Temperature: 36
- [caspase-9(Enzyme) wildtype]

Caspase_3 + Caspase_9 -> Caspase_9 + Caspase_3_cleaved		 (( (( (cytosol * k2) ) * C3) ) * C9) buffer: *
PH: 7
Temperature: 36

Pathways

pathway id name
Reactome:R-DME-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases
Reactome:R-MMU-111459 Activation of caspases through apoptosome-mediated cleavage
Reactome:R-MMU-111458 Formation of apoptosome
Reactome:R-MMU-111461 Cytochrome c-mediated apoptotic response
Reactome:R-MMU-9627069 Regulation of the apoptosome activity
Reactome:R-HSA-9627069 Regulation of the apoptosome activity
Reactome:R-HSA-109606 Intrinsic Pathway for Apoptosis
Reactome:R-HSA-111471 Apoptotic factor-mediated response
Reactome:R-HSA-111469 SMAC, XIAP-regulated apoptotic response
Reactome:R-HSA-9006925 Intracellular signaling by second messengers
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer
Reactome:R-MMU-5357801 Programmed Cell Death
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-MMU-198323 AKT phosphorylates targets in the cytosol
Reactome:R-DME-5633008 TP53 Regulates Transcription of Cell Death Genes
Reactome:R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway
Reactome:R-HSA-418889 Ligand-independent caspase activation via DCC
Reactome:R-HSA-111459 Activation of caspases through apoptosome-mediated cleavage
Reactome:R-MMU-109606 Intrinsic Pathway for Apoptosis
Reactome:R-MMU-1257604 PI3K/AKT Signaling
Reactome:R-DME-74160 Gene expression (Transcription)
Reactome:R-DME-73857 RNA Polymerase II Transcription
Reactome:R-DME-3700989 Transcriptional Regulation by TP53
Reactome:R-HSA-5357801 Programmed Cell Death
Reactome:R-HSA-111461 Cytochrome c-mediated apoptotic response
Reactome:R-HSA-1257604 PI3K/AKT Signaling
Reactome:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
Reactome:R-MMU-109581 Apoptosis
Reactome:R-DME-212436 Generic Transcription Pathway
Reactome:R-HSA-109581 Apoptosis
Reactome:R-HSA-111458 Formation of apoptosome
Reactome:R-HSA-111464 SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-HSA-198323 AKT phosphorylates targets in the cytosol
Reactome:R-HSA-2219528 PI3K/AKT Signaling in Cancer
Reactome:R-MMU-5357769 Caspase activation via extrinsic apoptotic signalling pathway
Reactome:R-MMU-418889 Ligand-independent caspase activation via DCC
Reactome:R-MMU-111471 Apoptotic factor-mediated response
Reactome:R-MMU-9006925 Intracellular signaling by second messengers
WikiPathways:WP1971 Integrated cancer pathway
WikiPathways:WP3959 DNA IR-double strand breaks and cellular response via ATM
WikiPathways:WP2263 Androgen receptor network in prostate cancer
WikiPathways:WP5182 Pro-survival signaling of neuroprotectin D1
PathBank:SMP0120910 D4-GDI Signaling Pathway
PathBank:SMP0066935 D4-GDI Signaling Pathway
PathBank:SMP0108163 Ras Signaling Pathway
PathBank:SMP0063784 Ras Signaling Pathway