EC: 3.4.13.18

cytosol nonspecific dipeptidase ()

enzyme lambda metabolic reaction experiment
- [Mn2+]

Carnosine + H2O -> L_Histidine + beta_Alanine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 3 mM Dithioerythritol, 3 mM Histidine
PH: 8.8
Temperature: 37
- [Mn2+]

H2O + beta_Alanyl_L_arginine -> beta_Alanine + Arginine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 3 mM Dithioerythritol, 3 mM Histidine
PH: 8.8
Temperature: 37
uniprot:Q96KP4 [Mn2+]

H2O + Carnosine -> L_Histidine + beta_Alanine		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris-sarcosine
PH: 9.5
Temperature: 30
uniprot:Q96KP4 [Mn2+]

H2O + L_Seryl_L_Glutamine -> L_Glutamine + L_Serine		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris-sarcosine
PH: 7.5
Temperature: 30

Pathways

pathway id name
BioCyc:HUMAN_PWY-4041 γ-glutamyl cycle
BioCyc:META_PWY0-1546 muropeptide degradation
BioCyc:ECO_PWY0-1546 muropeptide degradation
Reactome:R-BTA-9748784 Drug ADME
Reactome:R-MMU-9753281 APAP ADME
Reactome:R-RNO-9748784 Drug ADME
Reactome:R-BTA-9753281 APAP ADME
Reactome:R-RNO-9753281 APAP ADME
Reactome:R-HSA-9753281 APAP ADME
Reactome:R-MMU-9748784 Drug ADME
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-156590 Glutathione conjugation
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-RNO-156590 Glutathione conjugation
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-HSA-156580 Phase II - Conjugation of compounds
Reactome:R-MMU-156580 Phase II - Conjugation of compounds
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-BTA-174403 Glutathione synthesis and recycling
Reactome:R-HSA-156590 Glutathione conjugation
Reactome:R-MMU-156590 Glutathione conjugation
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-174403 Glutathione synthesis and recycling
Reactome:R-BTA-156580 Phase II - Conjugation of compounds
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-174403 Glutathione synthesis and recycling
Reactome:R-MMU-174403 Glutathione synthesis and recycling
Reactome:R-RNO-156580 Phase II - Conjugation of compounds
WikiPathways:WP5240 Lac-Phe pathway
PathBank:SMP0087314 Histidine Metabolism
PathBank:SMP0120713 Histidinemia
PathBank:SMP0087180 beta-Alanine Metabolism
PathBank:SMP0063599 beta-Alanine Metabolism
PathBank:SMP0120493 Histidinemia
PathBank:SMP0120558 Carnosinuria, Carnosinemia
PathBank:SMP0000044 Histidine Metabolism
PathBank:SMP0000191 Histidinemia
PathBank:SMP0087219 Histidine Metabolism
PathBank:SMP0063632 Histidine Metabolism
PathBank:SMP0120478 GABA-Transaminase Deficiency