EC: 1.5.3.13

N1-acetylpolyamine oxidase (N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming))

enzyme lambda metabolic reaction experiment
- [N1-Acetylspermine]

N1_Acetylspermidine + O2 + H2O -> 3_Acetamidopropanal + H2O2 + Putrescine
(( (( (cytosol * Vmpao) ) * aD) ) / (Kmadpao * (( (( (( (1 + (aD / Kmadpao)) ) + (aS / Kmaspao)) ) + (D / Kmdpao)) ) + (S / Kmspao)))) buffer: *
PH: 7
Temperature: 36
- [N1-Acetylspermidine]

O2 + N1_Acetylspermine + H2O -> 3_Acetamidopropanal + H2O2 + Spermidine
(( (( (cytosol * Vmpao) ) * aS) ) / (Kmaspao * (( (( (( (1 + (aD / Kmadpao)) ) + (aS / Kmaspao)) ) + (D / Kmdpao)) ) + (S / Kmspao)))) buffer: *
PH: 7
Temperature: 36

Pathways

pathway id name
BioCyc:HUMAN_PWY-6117 spermine and spermidine degradation I
BioCyc:META_PWY-6117 spermine and spermidine degradation I
Reactome:R-HSA-351202 Metabolism of polyamines
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-141334 PAOs oxidise polyamines to amines
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-351202 Metabolism of polyamines
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-141334 PAOs oxidise polyamines to amines
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-HSA-211945 Phase I - Functionalization of compounds
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-MMU-211945 Phase I - Functionalization of compounds
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-351200 Interconversion of polyamines
Reactome:R-HSA-140179 Amine Oxidase reactions
Reactome:R-MMU-351200 Interconversion of polyamines
Reactome:R-MMU-140179 Amine Oxidase reactions