EC: 1.3.8.1

short-chain acyl-CoA dehydrogenase (short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase)

enzyme lambda metabolic reaction experiment
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

2,6_Dichloroindophenol + Octanoyl_CoA -> Reduced_2,6_dichlorophenolindophenol + trans_Oct_2_enoyl_CoA		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

2,6_Dichloroindophenol + Hexanoyl_CoA -> Reduced_2,6_dichlorophenolindophenol + trans_Hex_2_enoyl_CoA		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

2,6_Dichloroindophenol + Pentanoyl_CoA -> Reduced_2,6_dichlorophenolindophenol + trans_Pent_2_enoyl_CoA		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

2,6_Dichloroindophenol + Heptanoyl_CoA -> trans_Hept_2_enoyl_CoA + Reduced_2,6_dichlorophenolindophenol		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

Butanoyl_CoA + 2,6_Dichloroindophenol -> Crotonoyl_CoA + Reduced_2,6_dichlorophenolindophenol		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25
uniprot:Q3ZBF6 [butyryl-CoA dehydrogenase(Enzyme) wildtype]

2,6_Dichloroindophenol + Propanoyl_CoA -> Acryloyl_CoA + Reduced_2,6_dichlorophenolindophenol		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 200 mM Potassium phosphate
PH: 7.6
Temperature: 25

Pathways

pathway id name
BioCyc:HUMAN_LEU-DEG2-PWY leucine degradation
BioCyc:META_PWY-6604 superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation
BioCyc:META_PWY-6594 superpathway of Clostridium acetobutylicum solventogenic fermentation
BioCyc:META_CENTFERM-PWY pyruvate fermentation to butanoate
BioCyc:META_PWY-7003 glycerol degradation to butanol
BioCyc:MTBH37RV_FAO-PWY fatty acid β-oxidation I
BioCyc:MOUSE_PWY3DJ-6 Leucine Catabolism
BioCyc:MOUSE_LEU-DEG2-PWY leucine degradation I
BioCyc:META_PWY-5327 superpathway of L-lysine degradation
BioCyc:META_PWY-6583 pyruvate fermentation to butanol I
BioCyc:META_PWY-6590 superpathway of Clostridium acetobutylicum acidogenic fermentation
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-HSA-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids
Reactome:R-HSA-70895 Branched-chain amino acid catabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids
Reactome:R-MMU-70895 Branched-chain amino acid catabolism
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-RNO-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA
Reactome:R-RNO-70895 Branched-chain amino acid catabolism
Reactome:R-BTA-70895 Branched-chain amino acid catabolism
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-HSA-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-MMU-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA
Reactome:R-RNO-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Reactome:R-MMU-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA
WikiPathways:WP5123 Mitochondrial fatty acid oxidation disorders
WikiPathways:WP4686 Leucine, isoleucine and valine metabolism
WikiPathways:WP2318 Fatty acid oxidation
PathBank:SMP0120662 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I
PathBank:SMP0120746 Saccharopinuria/Hyperlysinemia II
PathBank:SMP0120806 3-Hydroxyisobutyric Aciduria
PathBank:SMP0120822 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0120826 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0120854 Pyridoxine Dependency with Seizures
PathBank:SMP0120870 2-Aminoadipic 2-Oxoadipic Aciduria
PathBank:SMP0120440 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency
PathBank:SMP0120444 3-Methylglutaconic Aciduria Type IV
PathBank:SMP0120476 Ethylmalonic Encephalopathy
PathBank:SMP0120516 Maple Syrup Urine Disease
PathBank:SMP0120520 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0120589 Isovaleric Acidemia
PathBank:SMP0120605 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0120609 Trifunctional Protein Deficiency
PathBank:SMP0000032 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0000051 Fatty Acid Metabolism
PathBank:SMP0000173 beta-Ketothiolase Deficiency
PathBank:SMP0000199 Maple Syrup Urine Disease
PathBank:SMP0000384 Methylmalonate Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000235 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0000141 3-Methylglutaconic Aciduria Type IV
PathBank:SMP0000524 Isovaleric Acidemia
PathBank:SMP0000540 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0000568 Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD)
PathBank:SMP0087185 Butyrate Metabolism
PathBank:SMP0087234 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0087358 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
PathBank:SMP0120661 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency
PathBank:SMP0120665 3-Methylglutaconic Aciduria Type IV
PathBank:SMP0120745 Methylmalonic Aciduria
PathBank:SMP0120757 Propionic Acidemia
PathBank:SMP0120805 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
PathBank:SMP0120825 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0120439 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency
PathBank:SMP0120443 3-Methylglutaconic Aciduria Type III
PathBank:SMP0120459 beta-Ketothiolase Deficiency
PathBank:SMP0120503 Isovaleric Aciduria
PathBank:SMP0120523 Methylmalonate Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120588 Isobutyryl-CoA Dehydrogenase Deficiency
PathBank:SMP0120604 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0120632 Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD)
PathBank:SMP0000073 Butyrate Metabolism
PathBank:SMP0000138 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency
PathBank:SMP0000140 3-Methylglutaconic Aciduria Type III
PathBank:SMP0000238 Isovaleric Aciduria
PathBank:SMP0000185 Glutaric Aciduria Type I
PathBank:SMP0000523 Isobutyryl-CoA Dehydrogenase Deficiency
PathBank:SMP0000539 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0087172 Fatty Acid Metabolism
PathBank:SMP0087265 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
PathBank:SMP0063603 Butyrate Metabolism
PathBank:SMP0063641 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
PathBank:SMP0063689 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0120660 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency
PathBank:SMP0120664 3-Methylglutaconic Aciduria Type III
PathBank:SMP0120696 Ethylmalonic Encephalopathy
PathBank:SMP0120704 Glutaric Aciduria Type I
PathBank:SMP0120736 Maple Syrup Urine Disease
PathBank:SMP0120740 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0120808 Isovaleric Acidemia
PathBank:SMP0120812 Hyperlysinemia II or Saccharopinuria
PathBank:SMP0120824 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0120828 Trifunctional Protein Deficiency
PathBank:SMP0120441 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I
PathBank:SMP0120525 Methylmalonic Aciduria
PathBank:SMP0120537 Propionic Acidemia
PathBank:SMP0120586 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
PathBank:SMP0120606 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0000137 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency
PathBank:SMP0000237 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I
PathBank:SMP0000200 Methylmalonic Aciduria
PathBank:SMP0000521 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
PathBank:SMP0000541 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0000545 Trifunctional Protein Deficiency
PathBank:SMP0087280 Fatty Acid Metabolism
PathBank:SMP0087300 Lysine Degradation
PathBank:SMP0120663 3-Methylglutaconic Aciduria Type I
PathBank:SMP0120679 beta-Ketothiolase Deficiency
PathBank:SMP0120723 Isovaleric Aciduria
PathBank:SMP0120743 Methylmalonate Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120807 Isobutyryl-CoA Dehydrogenase Deficiency
PathBank:SMP0120811 Hyperlysinemia I, Familial
PathBank:SMP0120823 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0120851 Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD)
PathBank:SMP0120442 3-Methylglutaconic Aciduria Type I
PathBank:SMP0120587 3-Hydroxyisobutyric Aciduria
PathBank:SMP0120603 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0120607 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0000236 Propionic Acidemia
PathBank:SMP0000139 3-Methylglutaconic Aciduria Type I
PathBank:SMP0000181 Ethylmalonic Encephalopathy
PathBank:SMP0000480 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
PathBank:SMP0000522 3-Hydroxyisobutyric Aciduria
PathBank:SMP0000538 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0000542 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0000635 Valproic Acid Metabolism Pathway
PathBank:SMP0087267 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
PathBank:SMP0087287 Butyrate Metabolism
PathBank:SMP0087327 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0063589 Fatty Acid Metabolism