EC: 1.3.5.2

dihydroorotate dehydrogenase (quinone) ((S)-dihydroorotate:quinone oxidoreductase)

enzyme lambda metabolic reaction experiment
uniprot:Q5E9W3 [Barbiturate]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (( (E * kcat) ) * B) ) / (Km + (( (1 + (I / Kii)) ) * B))) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [Barbiturate]

Ubiquinone + L_Dihydroorotate -> Ubiquinol + Orotate		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Orotate + Ubiquinol		 (( (( (E * kcat) ) * A) ) / (Km + (( (1 + (I / Kii)) ) * A))) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Orotate + Ubiquinol		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Ubiquinol + Orotate		 (( (( (( (E * kcat) ) * A) ) * B) ) / (( (( (Km_A * B) ) + (Km_B * A)) ) + (A * B))) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Ubiquinol + Orotate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Ubiquinol + Orotate		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Menadione -> Menadiol + Orotate		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate_6'_methylester -> Ubiquinol + Orotate_6'_methylester		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Potassium phosphate, 0.1 % Triton X-100
PH: 7.8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [5-Methylorotate]

Ubiquinone + L_Dihydroorotate -> Ubiquinol + Orotate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [cis-5-Methyl dihydroorotate]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Potassium phosphate, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Ubiquinol + Orotate		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Potassium phosphate, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + Benzyl_S_dihydroorotate -> Ubiquinol + Benzyl_S_orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q5E9W3 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + Methyl_S_dihydroorotate -> Methyl_S_orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Potassium phosphate, 70 µM 2,6-Dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 37
uniprot:Q874I4 [2,6-Dichloroindophenol]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [2,6-Dichloroindophenol]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

2,6_Dichloroindophenol + L_Dihydroorotate -> Reduced_2,6_dichlorophenolindophenol + Orotate		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [dihydroorotate dehydrogenase (quinone)(Enzyme) mutant deltaNCa]

L_Dihydroorotate + 2,6_Dichloroindophenol -> Orotate + Reduced_2,6_dichlorophenolindophenol		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [Redoxal]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (Vmax / (1 + (I / IC50))) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [dihydroorotate dehydrogenase (quinone)(Enzyme) mutant deltaNCa]

L_Dihydroorotate + Decylubiquinone -> Decylubiquinol + Orotate		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [Brequinar]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (Vmax / (1 + (I / IC50))) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q874I4 [Redoxal]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (Vmax / (1 + (I / IC50))) buffer: 50 mM Tris/HCl, 150 mM KCl, 10% (v/v) glycerol, 0.1% (v/v) Triton X-100
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.06 mM 2,6-dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Orotate + Ubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.06 mM 2,6-dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Decylubiquinone + L_Dihydroorotate -> Decylubiquinol + Orotate		 (Vmax / (( (( (( (10 ^ (0 - pH)) ) / (10 ^ (0 - pKa1))) ) + (( (10 ^ (0 - pKa2)) ) / (10 ^ (0 - pH)))) ) + 1)) buffer: 50 mM Mes-HCl / Hepes-HCl / Tris-HCl, 150 mM KCl, 0.06 mM 2,6-dichloroindophenol, 0.1 % Triton X-100
PH: 5.55
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.06 mM 2,6-dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 30
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.06 mM 2,6-dichloroindophenol, 0.1 % Triton X-100
PH: 8
Temperature: 30
uniprot:Q02127 [2-Hydroxyethylidenecyanoacetic acid 4-trifluoromethyl anilide]

L_Dihydroorotate + Decylubiquinone -> Decylubiquinol + Orotate		 (( (Vmax * A) ) / (Km + (( (1 + (I / Kiu)) ) * A))) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [2-Hydroxyethylidenecyanoacetic acid 4-trifluoromethyl anilide]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (Vmax / (1 + (I / IC50))) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Ubiquinone -> Ubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Ubiquinone + L_Dihydroorotate -> Ubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Decylubiquinone -> Decylubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [2-Hydroxyethylidenecyanoacetic acid 4-trifluoromethyl anilide]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (( (Vmax * B) ) / (( (Km * (1 + (I / Kic))) ) + (( (1 + (I / Kiu)) ) * B))) buffer: 50 mM Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 8
Temperature: 30
uniprot:Q02127 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (Vmax / (( (1 + (( (10 ^ (0 - pH)) ) / (10 ^ (0 - pKa1)))) ) + (( (10 ^ (0 - pKa2)) ) / (10 ^ (0 - pH))))) buffer: 50 mM Mes/HCl or Hepes/HCl or Tris/HCl, 150 mM KCl, 0,1 % Triton X-100, 0.04 mM 2,6-dichloroindophenol
PH: 5.5
Temperature: 30
uniprot:Q63707 [D-Dihydroorotate]

L_Dihydroorotate + Menadione -> Orotate + Menadiol		 (( (Vmax * S1) ) / (( (Km * (1 + (I / Ki))) ) + S1)) buffer: 67 mM Tris-HCl, 1 mM KCN, 67 mM Cytochrome C
PH: 7.4
Temperature: 37
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Menadione + L_Dihydroorotate -> Orotate + Menadiol		 (( (Vmax * S1) ) / (( (Km * (1 + (I / Ki))) ) + S1)) buffer: 67 mM Tris-HCl, 1 mM KCN, 67 mM Cytochrome C
PH: 7.4
Temperature: 37
uniprot:Q63707 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Menadione + L_Dihydroorotate -> Menadiol + Orotate		 (( (Vmax * S1) ) / (Km + S1)) buffer: 67 mM Tris-HCl, 1 mM KCN, 67 mM Cytochrome C
PH: 7.4
Temperature: 37
uniprot:Q63707 [2,4-Dinitrophenol]

L_Dihydroorotate + Menadione -> Menadiol + Orotate		 (( (Vmax * S1) ) / (( (Km * (1 + (I / Ki))) ) + (S1 * (1 + (I / Ki))))) buffer: 67 mM Tris-HCl, 1 mM KCN, 67 mM Cytochrome C
PH: 7.4
Temperature: 37
uniprot:Q63707 [Barbiturate]

Menadione + L_Dihydroorotate -> Orotate + Menadiol		 (( (Vmax * S1) ) / (( (Km * (1 + (I / Ki))) ) + S1)) buffer: 67 mM Tris-HCl, 1 mM KCN, 67 mM Cytochrome C
PH: 7.4
Temperature: 37
uniprot:P59626 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

Menadione + L_Dihydroorotate -> Menadiol + Orotate		 (( (( (( (E * kcat) ) * A) ) * B) ) / (( (( (Ka * B) ) + (Kb * A)) ) + (A * B))) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P59626 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Menadione -> Orotate + Menadiol		 (( (( (E * kcat) ) * A) ) / (( (Ka * (1 + (I / Kis))) ) + A)) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P59626 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Menadione -> Menadiol + Orotate		 (( (( (( (E * kcat) ) * A) ) * B) ) / (( (( (Ka * B) ) + (Kb * A)) ) + (A * B))) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P59626 [Barbiturate]

Menadione + L_Dihydroorotate -> Orotate + Menadiol		 (( (( (E * kcat) ) * A) ) / (( (Ka * (1 + (I / Kis))) ) + A)) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P59626 [Barbiturate]

Menadione + L_Dihydroorotate -> Menadiol + Orotate		 (( (( (E * kcat) ) * A) ) / (Ka + (A * (1 + (I / Kii))))) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P59626 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype]

L_Dihydroorotate + Menadione -> Menadiol + Orotate		 (( (( (E * kcat) ) * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 0.1 M Tris, 0.05 mM 2,6- dichloroindophenol
PH: 7.5
Temperature: 25
uniprot:P32747 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype C-terminal His8-tagged]

L_Dihydroorotate + Decylubiquinone -> Decylubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30
uniprot:P32747 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype C-terminal His8-tagged]

Decylubiquinone + L_Dihydroorotate -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30
uniprot:Q6V3W9 [dihydroorotate dehydrogenase (quinone)(Enzyme) mutant N-terminal truncated (52 amino acids), C-terminal His8-tagged]

Decylubiquinone + L_Dihydroorotate -> Decylubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30
uniprot:Q6V3W9 [dihydroorotate dehydrogenase (quinone)(Enzyme) mutant N-terminal truncated (52 amino acids), C-terminal His8-tagged]

Decylubiquinone + L_Dihydroorotate -> Decylubiquinol + Orotate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30
uniprot:Q6V3W9 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype C-terminal His8-tagged]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30
uniprot:Q6V3W9 [dihydroorotate dehydrogenase (quinone)(Enzyme) wildtype C-terminal His8-tagged]

L_Dihydroorotate + Decylubiquinone -> Orotate + Decylubiquinol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 150 mM KCl, 0.1% Triton X-100, 60 µM 2,6-Dichlorophenolindophenol
PH: 8
Temperature: 30

Pathways

pathway id name
BioCyc:HUMAN_PWY-5686 UMP biosynthesis
BioCyc:META_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:VCHO_PWY-7790 UMP biosynthesis II
BioCyc:HPY_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HPY_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:CORYNE_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:HUMAN_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HUMAN_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:META_PWY-5686 UMP biosynthesis I
BioCyc:ECO_PWY-5686 UMP biosynthesis I
BioCyc:ARA_PWY-5686 UMP biosynthesis I
BioCyc:ARA_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:MTBH37RV_PWY-5686 UMP biosynthesis I
BioCyc:MTBH37RV_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HPY_PWY-5686 UMP biosynthesis I
BioCyc:ECOO157_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECOO157_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:SYNEL_PWY-5686 UMP biosynthesis
BioCyc:ECOL316407_PWY-5686 UMP biosynthesis
BioCyc:CORYNE_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:META_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ECO_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ARA_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:MTBH37RV_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ECOL316407_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ECO_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECOO157_PWY-5686 UMP biosynthesis
BioCyc:SYNEL_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:CORYNE_PWY-5686 UMP biosynthesis
WikiPathways:WP2472 Escherichia coli K-12 peripherome
PathBank:SMP0000959 Pyrimidine Metabolism
Reactome:R-DME-500753 Pyrimidine biosynthesis
Reactome:R-MMU-1430728 Metabolism
Reactome:R-PFA-500753 Pyrimidine biosynthesis
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-15869 Nucleotide metabolism
Reactome:R-DME-1430728 Metabolism
Reactome:R-HSA-8956320 Nucleotide biosynthesis
Reactome:R-MMU-8956320 Nucleotide biosynthesis
Reactome:R-RNO-8956320 Nucleotide biosynthesis
Reactome:R-SPO-500753 Pyrimidine biosynthesis
Reactome:R-DME-15869 Nucleotide metabolism
Reactome:R-HSA-500753 Pyrimidine biosynthesis
Reactome:R-MMU-500753 Pyrimidine biosynthesis
Reactome:R-PFA-1430728 Metabolism
Reactome:R-PFA-15869 Nucleotide metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-500753 Pyrimidine biosynthesis
Reactome:R-SPO-8956320 Nucleotide biosynthesis
Reactome:R-DME-8956320 Nucleotide biosynthesis
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-PFA-8956320 Nucleotide biosynthesis
Reactome:R-RNO-15869 Nucleotide metabolism
WikiPathways:WP4584 Biomarkers for pyrimidine metabolism disorders
WikiPathways:WP4225 Pyrimidine metabolism and related diseases
PathBank:SMP0120678 beta-Ureidopropionase Deficiency
PathBank:SMP0120750 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0121324 Pyrimidine Metabolism
PathBank:SMP0000178 Dihydropyrimidinase Deficiency
PathBank:SMP0120693 Dihydropyrimidinase Deficiency
PathBank:SMP0000046 Pyrimidine Metabolism
PathBank:SMP0000219 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0000202 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0087340 Pyrimidine Metabolism
PathBank:SMP0120727 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0000172 beta-Ureidopropionase Deficiency