EC: 1.14.11.73

[protein]-arginine 3-hydroxylase ([protein]-L-arginine,2-oxoglutarate:oxygen oxidoreductase (3R-hydroxylating))

enzyme lambda metabolic reaction experiment
uniprot:Q8N371 [Fe2+]

RPS6_peptide + 2_Oxoglutarate + O2 -> CO2 + Succinate + (3R)_3_Hydroxy_L_arginyl_peptide		 (( (( (kcat * E) ) * Co) ) / (Km + Co)) buffer: 50 mM HEPES-Na, 400 µM sodium-(+)-L-ascorbate
PH: 7.5
Temperature: 37
uniprot:Q8N371 [Fe2+]

RPS6_peptide + O2 + 2_Oxoglutarate -> (3R)_3_Hydroxy_L_arginyl_peptide + Succinate + CO2		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 50 mM HEPES-Na, 400 µM sodium-(+)-L-ascorbate
PH: 7.5
Temperature: 37
uniprot:Q8N371 [Fe2+]

RPS6_peptide + O2 + 2_Oxoglutarate -> CO2 + Succinate + (3R)_3_Hydroxy_L_arginyl_peptide		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 50 mM HEPES-Na, 400 µM sodium-(+)-L-ascorbate
PH: 7.5
Temperature: 37

Pathways

pathway id name
Reactome:R-RNO-9629569 Protein hydroxylation
Reactome:R-DME-9629569 Protein hydroxylation
Reactome:R-BTA-9629569 Protein hydroxylation
Reactome:R-HSA-9629569 Protein hydroxylation
Reactome:R-MMU-9629569 Protein hydroxylation
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-BTA-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-DME-392499 Metabolism of proteins
Reactome:R-DME-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-HSA-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-RNO-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-MMU-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation