EC: 6.3.4.21

nicotinate phosphoribosyltransferase (5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming))

enzyme lambda metabolic reaction experiment
uniprot:Q6XQN6 [ATP]

5_Phospho_alpha_D_ribose_1_diphosphate + Nicotinate -> Nicotinate_D_ribonucleotide + Diphosphate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES/KOH, 2.5 mM DTT
PH: 7.5
Temperature: 37
uniprot:Q6XQN6 [ATP]

Nicotinate + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + Nicotinate_D_ribonucleotide		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES/KOH, 2.5 mM DTT
PH: 7.5
Temperature: 37
uniprot:Q6XQN6 [Mg2+]

Nicotinate + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + Nicotinate_D_ribonucleotide		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES/KOH, 2.5 mM DTT
PH: 7.5
Temperature: 37
uniprot:Q6XQN6 [Mg2+]

Nicotinate + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + Nicotinate_D_ribonucleotide		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES/KOH, 2.5 mM DTT
PH: 7.5
Temperature: 37

Pathways

pathway id name
BioCyc:YEAST_PWY3O-4107 NAD salvage pathway
BioCyc:ARA_PWY-5381 pyridine nucleotide cycling (plants)
BioCyc:ECOO157_PYRIDNUCSAL-PWY NAD salvage pathway I
BioCyc:META_PYRIDNUCSAL-PWY NAD salvage pathway I (PNC VI cycle)
BioCyc:MTBH37RV_PYRIDNUCSAL-PWY NAD salvage pathway I (PNC VI cycle)
BioCyc:MTBCDC1551_PYRIDNUCSAL-PWY NAD salvage pathway I
BioCyc:ECO_PYRIDNUCSAL-PWY NAD salvage pathway I (PNC VI cycle)
BioCyc:BSUB_PYRIDNUCSAL-PWY NAD salvage pathway I (PNC VI cycle)
BioCyc:MOUSE_PYRNUCYC-PWY pyridine nucleotide cycling
BioCyc:ECOL316407_PYRIDNUCSAL-PWY NAD salvage pathway I
WikiPathways:WP2472 Escherichia coli K-12 peripherome
PathBank:SMP0000850 NAD Salvage
PlantCyc:ARA_PWY-5381 pyridine nucleotide cycling (plants)
PlantCyc:ARA_PWY3O-4107 NAD salvage pathway V (PNC V cycle)
Reactome:R-CEL-196807 Nicotinate metabolism
Reactome:R-DRE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DDI-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DME-196807 Nicotinate metabolism
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-RNO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-CEL-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DRE-196854 Metabolism of vitamins and cofactors
Reactome:R-DDI-196854 Metabolism of vitamins and cofactors
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DRE-196807 Nicotinate metabolism
Reactome:R-DDI-196807 Nicotinate metabolism
Reactome:R-HSA-196807 Nicotinate metabolism
Reactome:R-MMU-196807 Nicotinate metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-196807 Nicotinate metabolism
Reactome:R-CEL-1430728 Metabolism
Reactome:R-CEL-196854 Metabolism of vitamins and cofactors
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DME-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-1430728 Metabolism
PathBank:SMP0121074 Nicotinate and Nicotinamide Metabolism
PathBank:SMP0002338 NAD Metabolism