EC: 3.4.21.22

coagulation factor IXa ()

enzyme lambda metabolic reaction experiment
- [Ca2+]

Factor_X -> Factor_Xa		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer:
PH: 7
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.4 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [Ca2+]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin
PH: 7.9
Temperature: 37
uniprot:P00741 [coagulation factor IXa(Enzyme) wildtype]

Factor_X -> Factor_Xa		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 175 mM NaCl, 0.5 mg/ml ovalbumin, 5 mM EDTA
PH: 7.9
Temperature: 37

Pathways

pathway id name
Reactome:R-HSA-9673202 Defective F9 variant does not activate FX
Reactome:R-HSA-9672396 Defective cofactor function of FVIIIa variant
Reactome:R-HSA-9671793 Diseases of hemostasis
Reactome:R-HSA-9662001 Defective factor VIII causes hemophilia A
Reactome:R-HSA-9668250 Defective factor IX causes hemophilia B
Reactome:R-HSA-9651496 Defects of Formation of Fibrin Clot (Clotting Cascade)
Reactome:R-HSA-9672383 Defective factor IX causes thrombophilia
Reactome:R-HSA-9629569 Protein hydroxylation
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-140837 Intrinsic Pathway of Fibrin Clot Formation
Reactome:R-MMU-159740 Gamma-carboxylation of protein precursors
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Reactome:R-RNO-109582 Hemostasis
Reactome:R-RNO-140834 Extrinsic Pathway of Fibrin Clot Formation
Reactome:R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation
Reactome:R-HSA-159740 Gamma-carboxylation of protein precursors
Reactome:R-MMU-140834 Extrinsic Pathway of Fibrin Clot Formation
Reactome:R-MMU-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-159740 Gamma-carboxylation of protein precursors
Reactome:R-RNO-140877 Formation of Fibrin Clot (Clotting Cascade)
Reactome:R-HSA-109582 Hemostasis
Reactome:R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade)
Reactome:R-HSA-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-MMU-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Reactome:R-RNO-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-RNO-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins
Reactome:R-RNO-140837 Intrinsic Pathway of Fibrin Clot Formation
Reactome:R-HSA-140834 Extrinsic Pathway of Fibrin Clot Formation
Reactome:R-HSA-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Reactome:R-MMU-109582 Hemostasis
Reactome:R-MMU-140877 Formation of Fibrin Clot (Clotting Cascade)
Reactome:R-MMU-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
Reactome:R-MMU-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins
Reactome:R-RNO-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
WikiPathways:WP5186 Vitamin K metabolism and activation of dependent proteins
PathBank:SMP0000274 Heparin Action Pathway
PathBank:SMP0000278 Lepirudin Action Pathway
PathBank:SMP0000282 Streptokinase Action Pathway
PathBank:SMP0000286 Aminocaproic Acid Action Pathway
PathBank:SMP0000269 Acenocoumarol Action Pathway
PathBank:SMP0000273 Fondaparinux Action Pathway
PathBank:SMP0000277 Bivalirudin Action Pathway
PathBank:SMP0000281 Anistreplase Action Pathway
PathBank:SMP0000285 Reteplase Action Pathway
PathBank:SMP0000268 Warfarin Action Pathway
PathBank:SMP0000656 Dicoumarol Action Pathway
PathBank:SMP0000275 Ardeparin Action Pathway
PathBank:SMP0000279 Ximelagatran Action Pathway
PathBank:SMP0000283 Tenecteplase Action Pathway
PathBank:SMP0000287 Tranexamic Acid Action Pathway
PathBank:SMP0000270 Dicumarol Action Pathway
PathBank:SMP0000586 Coagulation
PathBank:SMP0000272 Enoxaparin Action Pathway
PathBank:SMP0000276 Argatroban Action Pathway
PathBank:SMP0000280 Alteplase Action Pathway
PathBank:SMP0000284 Urokinase Action Pathway
PathBank:SMP0000288 Aprotinin Action Pathway
PathBank:SMP0000271 Phenprocoumon Action Pathway
PathBank:SMP0000655 Phenindione Action Pathway