EC: 1.1.99.1

choline dehydrogenase (choline:acceptor 1-oxidoreductase)

enzyme lambda metabolic reaction experiment
- [choline dehydrogenase(Enzyme) wildtype]

O2 + 2 Choline -> 2 Betaine_aldehyde + 2 H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 40 mM sodium bisulfite, 80 mM sodium phosphate
PH: 7.5
Temperature: 37
- [choline dehydrogenase(Enzyme) wildtype]

H2O + O2 + Betaine_aldehyde -> Betaine + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 40 mM sodium bisulfite, 80 mM sodium phosphate
PH: 7.5
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY66-414 superpathway of choline degradation to L-serine
BioCyc:ECOO157_BETSYN-PWY glycine betaine biosynthesis I (Gram-negative bacteria)
BioCyc:ECOO157_CHOLINE-BETAINE-ANA-PWY choline degradation I
BioCyc:AGRO_BETSYN-PWY glycine betaine biosynthesis I (Gram-negative bacteria)
BioCyc:META_CHOLINE-BETAINE-ANA-PWY choline degradation I
BioCyc:ECO_BETSYN-PWY glycine betaine biosynthesis I (Gram-negative bacteria)
BioCyc:AGRO_P542-PWY choline-O-sulfate degradation
BioCyc:ECOL316407_BETSYN-PWY glycine betaine biosynthesis I (Gram-negative bacteria)
BioCyc:AGRO_CHOLINE-BETAINE-ANA-PWY choline degradation I
BioCyc:HUMAN_CHOLINE-BETAINE-ANA-PWY choline degradation
BioCyc:META_P542-PWY choline-O-sulfate degradation
BioCyc:META_BETSYN-PWY glycine betaine biosynthesis I (Gram-negative bacteria)
Reactome:R-HSA-6798163 Choline catabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-6798163 Choline catabolism
Reactome:R-RNO-6798163 Choline catabolism
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP4288 MTHFR deficiency
PathBank:SMP0120718 Hypermethioninemia
PathBank:SMP0108776 Sarcosine Oncometabolite Pathway
PathBank:SMP0000177 Cystathionine beta-Synthase Deficiency
PathBank:SMP0000340 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
PathBank:SMP0002313 Sarcosine Oncometabolite Pathway
PathBank:SMP0087342 Methionine Metabolism
PathBank:SMP0063600 Betaine Metabolism
PathBank:SMP0120853 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0120471 Cystathionine beta-Synthase Deficiency
PathBank:SMP0120487 Glycine N-Methyltransferase Deficiency
PathBank:SMP0120519 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120527 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0000033 Methionine Metabolism
PathBank:SMP0000222 Glycine N-Methyltransferase Deficiency
PathBank:SMP0087285 Betaine Metabolism
PathBank:SMP0063637 Methionine Metabolism
PathBank:SMP0108762 Sarcosine Oncometabolite Pathway
PathBank:SMP0120634 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0000123 Betaine Metabolism
PathBank:SMP0000341 Hypermethioninemia
PathBank:SMP0000221 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120691 Cystathionine beta-Synthase Deficiency
PathBank:SMP0120707 Glycine N-Methyltransferase Deficiency
PathBank:SMP0120739 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120747 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0120498 Hypermethioninemia
PathBank:SMP0000214 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0000570 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type