EC: 2.1.1.4

acetylserotonin O-methyltransferase (S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q6EPG8 [acetylserotonin O-methyltransferase(Enzyme) wildtype ASMT1]

S_Adenosyl_L_methionine + N_Acetylserotonin -> Melatonin + S_Adenosyl_L_homocysteine
(( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 7.7
Temperature: 55

Pathways

pathway id name
BioCyc:HUMAN_PWY66-401 superpathway of tryptophan utilization
BioCyc:META_PWY-7995 tricin biosynthesis
BioCyc:META_PWY-6631 tricetin methylation
BioCyc:META_PWY-6232 chrysoeriol biosynthesis
BioCyc:ARA_PWY-5765 1,3,5-trimethoxybenzene biosynthesis
BioCyc:HUMAN_PWY-6030 serotonin and melatonin biosynthesis
BioCyc:META_PWY-6030 serotonin and melatonin biosynthesis
Plant Reactome:R-OSA-9826798 Gravitropism under normal or artificial gravity environments
Plant Reactome:R-OSA-9928372 Root gravitropism
Plant Reactome:R-OSA-9916190 Root angle formation: elongation and curvature response
Plant Reactome:R-OSA-8932729 Responses to stimuli: abiotic stimuli and stresses
Plant Reactome:R-OSA-9609573 Tricin biosynthesis
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2744344 Secondary metabolism
PlantCyc:ORYZA_PWY-7995 tricin biosynthesis
PlantCyc:ORYZA_PWY-6199 quercetin sulfate biosynthesis
PlantCyc:PLANT_PWY-7995 tricin biosynthesis
PlantCyc:ORYZA_PWY-6631 tricetin methylation
PlantCyc:ARA_PWY-6030 serotonin and melatonin biosynthesis
PlantCyc:ORYZA_PWY-6232 chrysoeriol biosynthesis
PlantCyc:ORYZA_PWY-6064 methylquercetin biosynthesis
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-HSA-209776 Metabolism of amine-derived hormones
Reactome:R-HSA-209931 Serotonin and melatonin biosynthesis
Reactome:R-MMU-209776 Metabolism of amine-derived hormones
Reactome:R-MMU-209931 Serotonin and melatonin biosynthesis
Reactome:R-RNO-209776 Metabolism of amine-derived hormones
Reactome:R-RNO-209931 Serotonin and melatonin biosynthesis
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-BTA-209776 Metabolism of amine-derived hormones
Reactome:R-BTA-209931 Serotonin and melatonin biosynthesis
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP4156 Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine
PathBank:SMP0012025 Flavone and Flavonol Biosynthesis
PathBank:SMP0000063 Tryptophan Metabolism